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- 13:25, 24 October 2025 Bcell Epitope prediction (hist | edit) [6,486 bytes] Carol (talk | contribs) (Created page with "We want to look for epitopes on the HIV GP120 protein. We will use both sequence-based and structure-based methods. Input data. Go to the pdb homepage and look for the pdb entry 4LSP. It is GP120 complexed with a broadly neutralizing antibody. These antibodies are extremely powerful, since they are effective against many different strains. Q1: Download both the structure (pdb) and the sequence (fasta) of the proteins in this entry. Which proteins are in chain G, L and...")
- 13:12, 24 October 2025 Epitope prediction (hist | edit) [7,333 bytes] Carol (talk | contribs) (Created page with "'''B-cell epitope prediction exercise''' VEGF (vascular endothelial growth factor) is a target in cancer therapies, being the protein responsible for vascularization of tumoral tissue. The murine anti-VEGF antibody has been proved to be effective in blocking VEGF, but it is immunogenic. The Bevacizumab is the commercial, humanized version of the antibody. Let’s reproduce its humanization. Anti-VEGF Humanization The sequence of the murine antibody is: >Light chai...")
- 17:12, 20 October 2025 Antibody Modelling (hist | edit) [7,336 bytes] Carol (talk | contribs) (Created page with "'''Humanization of the anti-VEGF antibody''' VEGF (vascular endothelial growth factor) is a target in cancer therapies, being the protein responsible for vascularization of tumoral tissue. The murine anti-VEGF antibody has been proved to be effective in blocking VEGF, but it is immunogenic. The Bevacizumab is the commercial, humanized version of the antibody. Let’s reproduce its humanization. Anti-VEGF Humanization The sequence of the murine antibody is: >Light c...")
- 13:10, 7 August 2025 22145 Immunological Bioinformatics Course Programme Fall 2025 (hist | edit) [12,935 bytes] Carol (talk | contribs) (Created page with "== General information == === Where and when === Wednesday from 8 to 12 in '''building 208, holdlokale 3/065''', starting on '''Wednesday, Sep 4 at 8:00'''. === Teachers === * [https://www.dtu.dk/Person/cwis?id=142840&entity=profile Carolina Barra Quaglia] — Associate professor, course responsible. * [https://www.dtu.dk/person/morten-nielsen?id=5973&entity=profile Morten Nielsen] — Professor, course responsible. === Teaching assistant === * [https://w...")