User contributions for Carol

18:3018:30, 4 November 2025 diff hist +8,699‎ N Bcell Epitope prediction answers ‎ Created page with "'''B-cell epitope prediction — Why do some flu vaccines miss? Influenza A hemagglutinin (HA) has two very different antibody targets: the variable head and the conserved stem. Head-binding antibodies often lose potency as the virus drifts; stem-binding broadly neutralizing antibodies (bnAbs) can resist drift. Can standard sequence-based and structure-based B-cell epitope predictors tell these stories apart? '''Part A, Get your bearings in PyMOL (find the ground truth..." current

14:3014:30, 28 October 2025 diff hist +1‎ Bcell Epitope prediction ‎No edit summary current
14:2914:29, 28 October 2025 diff hist +66‎ Bcell Epitope prediction ‎No edit summary
14:2914:29, 28 October 2025 diff hist +8‎ Bcell Epitope prediction ‎No edit summary
14:2814:28, 28 October 2025 diff hist +22‎ Bcell Epitope prediction ‎No edit summary

14:5914:59, 24 October 2025 diff hist +9‎ Bcell Epitope prediction ‎No edit summary
14:5814:58, 24 October 2025 diff hist +655‎ Bcell Epitope prediction ‎No edit summary
14:4914:49, 24 October 2025 diff hist +1‎ Bcell Epitope prediction ‎No edit summary
14:3514:35, 24 October 2025 diff hist 0‎ Bcell Epitope prediction ‎No edit summary
14:3514:35, 24 October 2025 diff hist +2‎ Bcell Epitope prediction ‎No edit summary
14:3414:34, 24 October 2025 diff hist +1,118‎ Bcell Epitope prediction ‎No edit summary
13:4113:41, 24 October 2025 diff hist +2,006‎ Bcell Epitope prediction ‎No edit summary
12:2512:25, 24 October 2025 diff hist +2,695‎ N Bcell Epitope prediction ‎ Created page with "We want to look for epitopes on the HIV GP120 protein. We will use both sequence-based and structure-based methods. Input data. Go to the pdb homepage and look for the pdb entry 4LSP. It is GP120 complexed with a broadly neutralizing antibody. These antibodies are extremely powerful, since they are effective against many different strains. Q1: Download both the structure (pdb) and the sequence (fasta) of the proteins in this entry. Which proteins are in chain G, L and..."
12:1212:12, 24 October 2025 diff hist +7,333‎ N Epitope prediction ‎ Created page with "'''B-cell epitope prediction exercise''' VEGF (vascular endothelial growth factor) is a target in cancer therapies, being the protein responsible for vascularization of tumoral tissue. The murine anti-VEGF antibody has been proved to be effective in blocking VEGF, but it is immunogenic. The Bevacizumab is the commercial, humanized version of the antibody. Let’s reproduce its humanization. Anti-VEGF Humanization The sequence of the murine antibody is: >Light chai..." current

16:1216:12, 20 October 2025 diff hist +7,336‎ N Antibody Modelling ‎ Created page with "'''Humanization of the anti-VEGF antibody''' VEGF (vascular endothelial growth factor) is a target in cancer therapies, being the protein responsible for vascularization of tumoral tissue. The murine anti-VEGF antibody has been proved to be effective in blocking VEGF, but it is immunogenic. The Bevacizumab is the commercial, humanized version of the antibody. Let’s reproduce its humanization. Anti-VEGF Humanization The sequence of the murine antibody is: >Light c..." current