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- 22:09, 29 September 2026 Exercise:AllergenicityPrediction ans (hist | edit) [9,689 bytes] Carol (talk | contribs) (Created page with "== Answers == === Get the Data and Filter It === *'''Q1A:''' What would be your first approach to determine whether brown algae contain potential allergens? Find one database containing experimentally characterized allergens. Consider what biological information you would search for and what properties of the proteins might provide evidence of allergenic potential. '''Answer:''' *'''Q1B:''' Now imagine that no computational predictor specifically designed for allerg...")
- 18:35, 29 September 2026 Exercise:AllergenicityPrediction (hist | edit) [9,461 bytes] Carol (talk | contribs) (Created page with "Exercise written by Carolina Barra Quaglia == Introduction == Immunopeptidomics experiments can identify thousands of peptides presented on the cell surface by MHC molecules. However, because an individual can express several different HLA alleles, it is often not immediately clear which HLA molecule is responsible for presenting each peptide. In addition, immunopeptidomics datasets may contain co-purified peptides that are not true MHC ligands. In this exercise, we w...")
- 19:57, 22 September 2026 Exercise:AntigenProcessing ans (hist | edit) [11,015 bytes] Carol (talk | contribs) (Created page with " *'''Q1: How many epitopes do you find with the initial filter?''' *'''Q2: Do you agree with calling these peptides epitopes? Why?''' Now refine your search by including only '''mass-spectrometry assays''' on '''HLA-DR restriction alleles'''. From the '''References''' tab, select the publication from the ''Journal of Proteome Research'' from 2017 by Wang et al. *'''Q3: How many eluted ligands did they find in this study?''' Under the '''Assays''' tab, select '''MHC...")
- 17:29, 22 September 2026 Exercise:AntigenProcessing (hist | edit) [11,818 bytes] Carol (talk | contribs) (Created page with "== MHC Motif Deconvolution == Immunopeptidomics is currently used in several biomedical applications, including neo-epitope discovery in oncology, protein-drug immunogenicity assessment, as well as next-generation vaccine development. Immunopeptidome data are highly complex given the expression of multiple HLA alleles on the cell membrane and the presence of co-immunoprecipitated contaminants, which is an inherent drawback of the immunopeptidomic workflow. To resolve t...")
- 11:47, 6 August 2026 22145 Immunological Bioinformatics Course Programme Fall 2026 (hist | edit) [8,708 bytes] Carol (talk | contribs) (Created page with "== General information == === Where and when === Wednesday from 9 to 12 in '''building 208, holdlokale 3/065''', starting on '''Wednesday, Sep 3 at 9:00'''. Classess will start at 9am unless specified. The first hour of the course will be dedicated to course-preparation. Including some videos or paper reading material === Teachers === * [https://www.dtu.dk/Person/cwis?id=142840&entity=profile Carolina Barra Quaglia] — Associate professor, course responsible. *...")