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- 16:46, 20 March 2024 Single cell technologies for T-cell epitopes (hist | edit) [11,345 bytes] WikiSysop (talk | contribs) (Created page with "'''It is the intention with the following exercises, that you discuss and solve the following tasks and questions in your groups, so talk to each other for mutual benefit''' = Introduction = The purpose of this exercise is to get a feeling with T-cell CDR3 sequence data and to try to make predictions on which sequences will bind a specific peptide. We will here use to approaches for predictions: a naive 'database look-up' approach and a neural network approach. With th...")
- 16:46, 20 March 2024 IEDB (hist | edit) [16,575 bytes] WikiSysop (talk | contribs) (Created page with " == Immune Epitope DataBase (IEDB) Exercises == ---- The Immune Epitope DataBase (IEDB) is a very useful resource for researchers of immunology and immunoinformatics. It is a highly organized database of epitopes(or more precisely: epitope assay results) that has a user friendly search interface. It is maintained by the La Jolla Institute for Allergy and Immunology and has a dedicated team of curators and bioinformatitians that have mined the immunological literature. T...")
- 16:43, 20 March 2024 Protein Drug Deimmunization (hist | edit) [10,211 bytes] WikiSysop (talk | contribs) (Created page with "== Protein Drug Deimmunization - Exercise == ---- Over the past few decades, biologics have gone from being experimental treatment options to standard care. They are very targeted and useful molecules in health care, but they come with their own immunological challenges. If a biologic is recognized as foreign by the immune system, Anti-Drug Antibodies can be formed that neutralize the biologic and render it useless. Deimmunization provides a potential solution to this...")
- 16:42, 20 March 2024 Antibody Humanization (hist | edit) [7,336 bytes] WikiSysop (talk | contribs) (Created page with "'''Humanization of the anti-VEGF antibody''' VEGF (vascular endothelial growth factor) is a target in cancer therapies, being the protein responsible for vascularization of tumoral tissue. The murine anti-VEGF antibody has been proved to be effective in blocking VEGF, but it is immunogenic. The Bevacizumab is the commercial, humanized version of the antibody. Let’s reproduce its humanization. Anti-VEGF Humanization The sequence of the murine antibody is: >Light c...")
- 16:41, 20 March 2024 Antibody Structure Prediction and Analysis (hist | edit) [3,022 bytes] WikiSysop (talk | contribs) (Created page with " == Antibody modeling == Requirements: [https://pymol.org/2/ Pymol] Download the version for your OS, then use the license file provided by the teachers '''Modeling of CLL antibody''' From the [http://www.cbs.dtu.dk/courses/27485.imm/VDJ_Exercise/rearrangements.txt rearrangements file], select the SI35 light and heavy chains. Translate the nucleic acid sequences to protein sequences (use a service of your choice, e.g. expasy or virtual ribosome). Go to the [http...")
- 16:40, 20 March 2024 Micro Project on Basic Immunology (hist | edit) [3,377 bytes] WikiSysop (talk | contribs) (Created page with "Make sure to read through all of this page ''before'' starting the micro-project == Background == Immunological bioinformatics is annotated as a [https://kurser.dtu.dk/course/22145 MSc/PhD eligible course], meaning that you will most likely be at the end of your studies when taking this course or you may be a PhD student. Today you will do active learning-work with a learning method called "Inquiry based learning", which is quite close to the way a researcher works, th...")
- 16:15, 20 March 2024 27685 Course programme 2017 (hist | edit) [11,856 bytes] WikiSysop (talk | contribs) (Created page with "=Immunological Bioinformatics - #27685= [http://wiki.bio.dtu.dk/teachingmaterials/index.php/Course27685 '''Course homepage'''] '''Information for participants''' '''GENERAL DAILY SCHEDULE''' Lectures will be from 9 - 12 am, Lunch from 12 - 13, Exercises from 13 - 17 pm. '''PLACE: DTU Building 210 room 162 ''' Classes will be a mixture of lectures and group work. Most of the group work will consist of '''computer exercises''' (bring your own laptop). Please note...")
- 16:15, 20 March 2024 36685 Immunological Bioinformatics Course Program January 2018 (hist | edit) [18,275 bytes] WikiSysop (talk | contribs) (Created page with " =Information for Course Attendees= The official course site can be [http://teaching.healthtech.dtu.dk/36685/index.php/36685_-_Immunological_Bioinformatics found here] '''General Daily Schedule''' * 09.00 - 12.00 Lectures * 12.00 - 13.00 Lunch * 13.00 - 17.00 Exercises Classes will be a mixture of lectures and group work. Most of the group work will consist of computer exercises (students are required to bring their own laptop). All literature will be available throu...")
- 16:14, 20 March 2024 36685 Immunological Bioinformatics Course Program January 2019 (hist | edit) [14,513 bytes] WikiSysop (talk | contribs) (Created page with "=Information for Course Attendees= Main page for course site can be found [http://teaching.healthtech.dtu.dk/36685/index.php/36685_-_Immunological_Bioinformatics here]. Please note, that the program can be subject to changes or updates. Make sure to reload the page, to get the newest version of the program. '''Course responsible and main lecturers''' * [https://www.dtu.dk/english/service/phonebook/person?id=22554&tab=2&qt=dtupublicationquery Postdoc Leon Eyrich Jessen]...")
- 16:14, 20 March 2024 22145 Immunological Bioinformatics Course Programme January 2020 (hist | edit) [14,708 bytes] WikiSysop (talk | contribs) (Created page with "==Information for Course Participants== '''Course Format''' * Classes will be a mixture of lectures and group work * Most of the group work will consist of computer exercises, students are required to bring their own laptop * All learning resources will be available through DTU inside or this site * Expected time usage: [https://www.dtu.dk/english/Education/Course-base 1 ECTS point equals approx. 28 hours], this translates to an expected time usage of ~10 hours/day for...")
- 12:28, 20 March 2024 22145 Immunological Bioinformatics Course Programme January 2021 (hist | edit) [21,734 bytes] WikiSysop (talk | contribs) (Created page with "= COURSE PLAN FOR 2021 = ==EXAM== The pdf with the exam will be uploaded here on Friday January 22nd, 13 - 15hs <!--Exam--> '''Guidelines''' * The exam will be made available at the wiki at 13.00hs. Upload a '''pdf''' with your answers '''no later than 15.00hs on DTU inside''' written exam assignment. * You must connect at Zoom 5 minutes before the exam, and have the '''camera turned ON during the whole exam'''. Failing to meet this requireme...")
- 12:18, 20 March 2024 22145 - Immunological Bioinformatics (hist | edit) [3,788 bytes] WikiSysop (talk | contribs) (Created page with "right '''Course Programme''' <!-- * Fall 2023 --> '''About''' * '''Course responsible''' [https://www.dtu.dk/person/carolina-barra-quaglia?id=142840&entity=profile Carolina Barra Quaglia] — Associate professor, course responsible. [https://www.dtu.dk/person/morten-nielsen?id=5973&entity=profile Morten Nielsen] — Professor, course responsib...")
