Antibody Humanization: Revision history

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20 March 2024

  • curprev 15:4215:42, 20 March 2024‎ WikiSysop talk contribs‎ 7,336 bytes +7,336‎ Created page with "'''Humanization of the anti-VEGF antibody''' VEGF (vascular endothelial growth factor) is a target in cancer therapies, being the protein responsible for vascularization of tumoral tissue. The murine anti-VEGF antibody has been proved to be effective in blocking VEGF, but it is immunogenic. The Bevacizumab is the commercial, humanized version of the antibody. Let’s reproduce its humanization. Anti-VEGF Humanization The sequence of the murine antibody is: >Light c..."
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