LOCUS       AF004877               38682 bp    DNA     linear   PRI 01-JAN-1998
DEFINITION  Homo sapiens pro-alpha 2(I) collagen (COL1A2) gene, complete cds.
ACCESSION   AF004877
VERSION     AF004877.1  GI:2735714
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (sites)
  AUTHORS   Myers,J.C., Dickson,L.A., de Wet,W.J., Bernard,M.P., Chu,M.L., Di
            Liberto,M., Pepe,G., Sangiorgi,F.O. and Ramirez,F.
  TITLE     Analysis of the 3' end of the human pro-alpha 2(I) collagen gene.
            Utilization of multiple polyadenylation sites in cultured
            fibroblasts
  JOURNAL   J. Biol. Chem. 258 (16), 10128-10135 (1983)
  MEDLINE   83290853
   PUBMED   6309769
REFERENCE   2  (sites)
  AUTHORS   Dickson,L.A., de Wet,W., Di Liberto,M., Weil,D. and Ramirez,F.
  TITLE     Analysis of the promoter region and the N-propeptide domain of the
            human pro alpha 2(I) collagen gene
  JOURNAL   Nucleic Acids Res. 13 (10), 3427-3438 (1985)
  MEDLINE   85242047
   PUBMED   4011429
REFERENCE   3  (bases 2295 to 2501; 5144 to 5154; 5746 to 5760; 6411 to 6446;
            7558 to 7650; 8929 to 8982; 11919 to 11963; 12056 to 12109; 12202
            to 12255; 12562 to 12615; 13036 to 13089; 13613 to 13666; 15217 to
            15261; 15553 to 15606; 15706 to 15750; 16140 to 16193; 16692 to
            16790; 16934 to 16978; 17093 to 17191; 17612 to 17665; 17791 to
            17898; 18259 to 18312; 18426 to 18524; 19436 to 19849; 19953 to
            20051; 20452 to 20505; 21059 to 21112; 21263 to 21316; 21590 to
            21643; 22596 to 22640; 23773 to 23871; 25090 to 25197; 25867 to
            25920; 26854 to 26907; 27588 to 27641; 27746 to 27799; 27896 to
            28003; 28365 to 28418; 29217 to 29270; 30273 to 30434; 31647 to
            31754; 32427 to 32534; 32920 to 32973; 33060 to 33167; 33308 to
            33361; 33733 to 33840; 34316 to 34369; 34496 to 34603; 34936 to
            35194; 35602 to 35786; 36498 to 36740; 37554 to 38546)
  AUTHORS   de Wet,W., Bernard,M., Benson-Chanda,V., Chu,M.L., Dickson,L.,
            Weil,D. and Ramirez,F.
  TITLE     Organization of the human pro-alpha 2(I) collagen gene
  JOURNAL   J. Biol. Chem. 262 (33), 16032-16036 (1987)
  MEDLINE   88058962
   PUBMED   2824475
REFERENCE   4  (bases 1 to 38682)
  AUTHORS   Kuivaniemi,H., Tromp,G., Chu,M.L. and Prockop,D.J.
  TITLE     Structure of a full-length cDNA clone for the prepro alpha 2(I)
            chain of human type I procollagen. Comparison with the chicken gene
            confirms unusual patterns of gene conservation
  JOURNAL   Biochem. J. 252 (3), 633-640 (1988)
  MEDLINE   88339824
   PUBMED   3421913
REFERENCE   5  (bases 21113 to 21262; 21644 to 22595)
  AUTHORS   Tromp,G. and Prockop,D.J.
  TITLE     Single base mutation in the pro alpha 2(I) collagen gene that
            causes efficient splicing of RNA from exon 27 to exon 29 and
            synthesis of a shortened but in-frame pro alpha 2(I) chain
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 85 (14), 5254-5258 (1988)
  MEDLINE   88276936
   PUBMED   2839839
REFERENCE   6  (bases 12616 to 13035; 13090 to 13612)
  AUTHORS   Kuivaniemi,H., Sabol,C., Tromp,G., Sippola-Thiele,M. and
            Prockop,D.J.
  TITLE     A 19-base pair deletion in the pro-alpha 2(I) gene of type I
            procollagen that causes in-frame RNA splicing from exon 10 to exon
            12 in a proband with atypical osteogenesis imperfecta and in his
            asymptomatic mother
  JOURNAL   J. Biol. Chem. 263 (23), 11407-11413 (1988)
  MEDLINE   88298792
   PUBMED   3403536
REFERENCE   7  (bases 3716 to 3747)
  AUTHORS   Sherwood,A.L., Bottenus,R.E., Martzen,M.R. and Bornstein,P.
  TITLE     Structural and functional analysis of the first intron of the human
            alpha2(I) collagen encoding gene
  JOURNAL   Gene 89, 238-244 (1990)
REFERENCE   8  (sites)
  AUTHORS   Sherwood,A.L., Bottenus,R.E., Martzen,M.R. and Bornstein,P.
  TITLE     Structural and functional analysis of the first intron of the human
            alpha2(I) collagen encoding gene
  JOURNAL   Gene 89, 238-244 (1990)
REFERENCE   9  (bases 25921 to 26853)
  AUTHORS   Ganguly,A., Baldwin,C.T., Strobel,D., Conway,D., Horton,W. and
            Prockop,D.J.
  TITLE     Heterozygous mutation in the G+5 position of intron 33 of the
            pro-alpha 2(I) gene (COL1A2) that causes aberrant RNA splicing and
            lethal osteogenesis imperfecta. Use of carbodiimide methods that
            decrease the extent of DNA sequencing necessary to define an
            unusual mutation
  JOURNAL   J. Biol. Chem. 266 (18), 12035-12040 (1991)
  MEDLINE   91268084
   PUBMED   1711048
REFERENCE   10 (bases 1 to 38682)
  AUTHORS   Korkko,J.M., Earley,J.J., Ala-Kokko,L. and Prockop,D.J.
  TITLE     Analysis of the COL1A1 and COL1A2 Genes by CSGE and DNA Sequencing
            in 14 Patients with Mild OI (Type I). Identification of Common
            Sequences for Null Allele Mutations
  JOURNAL   Unpublished
REFERENCE   11 (bases 12256 to 12561)
  AUTHORS   Trummer,T., Schwemmle,S., Just,W., Glaeser,D. and Kennerknecht,I.
  TITLE     Complete nucleotide sequence of intron 9 of the human pro-alpha2(I)
            collagen gene
  JOURNAL   Unpublished
REFERENCE   12 (bases 14500 to 14716)
  AUTHORS   Pepe,G.
  TITLE     A highly polymorphic (ACT)n VNTR (variable nucleotide tandem
            repeats) locus inside intron 12 of COL1A2, one of the two genes
            involved in dominant osteogenesis imperfecta
  JOURNAL   Unpublished
REFERENCE   13 (bases 1 to 38682)
  AUTHORS   Korkko,J.M., Earley,J.J., De Paepe,A., Nuytinck,L., Ala-Kokko,L.
            and Prockop,D.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-MAY-1997) Center for Gene Therapy, Allegheny
            University of the Health Sciences, 245 North 15th St., Mail stop
            421, Philadelphia, PA 19130, USA
FEATURES             Location/Qualifiers
     source          1..38682
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
     gene            1..38518
                     /gene="COL1A2"
     promoter        1..2431
                     /gene="COL1A2"
     repeat_region   846..877
                     /citation=[10]
                     /rpt_type=tandem
                     /rpt_unit="ca"
     CAAT_signal     2209..2213
                     /gene="COL1A2"
     TATA_signal     2262..2267
                     /gene="COL1A2"
     CDS             join(2432..2501,5144..5154,5746..5760,6411..6446,
                     7558..7650,8929..8982,11919..11963,12056..12109,
                     12202..12255,12562..12615,13036..13089,13613..13666,
                     15217..15261,15553..15606,15706..15750,16140..16193,
                     16692..16790,16934..16978,17093..17191,17612..17665,
                     17791..17898,18259..18312,18426..18524,19436..19489,
                     19953..20051,20452..20505,21059..21112,21263..21316,
                     21590..21643,22596..22640,23773..23871,25090..25197,
                     25867..25920,26854..26907,27588..27641,27746..27799,
                     27896..28003,28365..28418,29217..29270,30273..30434,
                     31647..31754,32427..32534,32920..32973,33060..33167,
                     33308..33361,33733..33840,34316..34369,34496..34603,
                     34936..35194,35602..35786,36498..36740,37554..37700)
                     /gene="COL1A2"
                     /codon_start=1
                     /product="pro-alpha 2(I) collagen"
                     /protein_id="AAB93981.1"
                     /db_xref="GI:2735715"
                     /translation="MLSFVDTRTLLLLAVTLCLATCQSLQEETVRKGPAGDRGPRGER
                     GPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPP
                     GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG
                     PQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGL
                     PGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAIGNAGPA
                     GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVG
                     AAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGP
                     PGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPR
                     GLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPVGARGEPGNIGFPGPKGPTGDPGKNG
                     DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPSGPAGE
                     VGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEP
                     GVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAHGAVG
                     APGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGE
                     RGGKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPP
                     GPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAG
                     PPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS
                     PGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPA
                     GKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGFKGHNGLQG
                     LPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGP
                     AGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLKSLNNQI
                     ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMEAIKVYCDFPTGETCI
                     RAQPENIPAKNWYRSSKDKKHVWLGETINAGSQFEYNVEGVTSKEMATQLAFMRLLAN
                     YASQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKK
                     TNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADHEFFVDIGPVCFK"
     exon            2432..2501
                     /gene="COL1A2"
                     /number=1
     protein_bind    2487..2500
                     /gene="COL1A2"
                     /note="putative"
                     /citation=[7]
                     /bound_moiety="NF1"
     intron          2502..5143
                     /gene="COL1A2"
                     /citation=[10]
                     /citation=[7]
                     /number=1
     protein_bind    3380..3386
                     /note="putative; bottom strand"
                     /bound_moiety="AP1"
     protein_bind    3407..3413
                     /gene="COL1A2"
                     /note="putative"
                     /citation=[7]
                     /bound_moiety="AP1"
     repeat_region   3716..3747
                     /citation=[7]
                     /rpt_type=tandem
                     /rpt_unit="gt"
     exon            5144..5154
                     /gene="COL1A2"
                     /number=2
     intron          5155..5745
                     /gene="COL1A2"
                     /citation=[10]
                     /number=2
     exon            5746..5760
                     /gene="COL1A2"
                     /number=3
     intron          5761..6410
                     /gene="COL1A2"
                     /citation=[10]
                     /number=3
     exon            6411..6446
                     /gene="COL1A2"
                     /number=4
     intron          6447..7557
                     /gene="COL1A2"
                     /citation=[10]
                     /number=4
     exon            7558..7650
                     /gene="COL1A2"
                     /number=5
     intron          7651..8928
                     /gene="COL1A2"
                     /citation=[10]
                     /number=5
     exon            8929..8982
                     /gene="COL1A2"
                     /number=6
     intron          8983..11918
                     /gene="COL1A2"
                     /citation=[10]
                     /number=6
     exon            11919..11963
                     /gene="COL1A2"
                     /number=7
     intron          11964..12055
                     /gene="COL1A2"
                     /citation=[10]
                     /number=7
     exon            12056..12109
                     /gene="COL1A2"
                     /number=8
     intron          12110..12201
                     /gene="COL1A2"
                     /citation=[10]
                     /number=8
     exon            12202..12255
                     /gene="COL1A2"
                     /number=9
     intron          12256..12561
                     /gene="COL1A2"
                     /citation=[11]
                     /number=9
     exon            12562..12615
                     /gene="COL1A2"
                     /number=10
     intron          12616..13035
                     /gene="COL1A2"
                     /number=10
     exon            13036..13089
                     /gene="COL1A2"
                     /number=11
     intron          13090..13612
                     /gene="COL1A2"
                     /number=11
     exon            13613..13666
                     /gene="COL1A2"
                     /number=12
     intron          13667..15216
                     /gene="COL1A2"
                     /citation=[10]
                     /citation=[12]
                     /number=12
     repeat_region   14708..14731
                     /citation=[12]
                     /rpt_type=tandem
                     /rpt_unit="ACT"
     exon            15217..15261
                     /gene="COL1A2"
                     /number=13
     intron          15262..15552
                     /gene="COL1A2"
                     /citation=[10]
                     /number=13
     exon            15553..15606
                     /gene="COL1A2"
                     /number=14
     intron          15607..15705
                     /gene="COL1A2"
                     /citation=[10]
                     /number=14
     exon            15706..15750
                     /gene="COL1A2"
                     /number=15
     intron          15751..16139
                     /gene="COL1A2"
                     /citation=[10]
                     /number=15
     exon            16140..16193
                     /gene="COL1A2"
                     /number=16
     intron          16194..16691
                     /gene="COL1A2"
                     /citation=[10]
                     /number=16
     exon            16692..16790
                     /gene="COL1A2"
                     /number=17
     intron          16791..16933
                     /gene="COL1A2"
                     /citation=[10]
                     /number=17
     exon            16934..16978
                     /gene="COL1A2"
                     /number=18
     intron          16979..17092
                     /gene="COL1A2"
                     /citation=[10]
                     /number=18
     exon            17093..17191
                     /gene="COL1A2"
                     /number=19
     intron          17192..17611
                     /gene="COL1A2"
                     /citation=[10]
                     /number=19
     exon            17612..17665
                     /gene="COL1A2"
                     /number=20
     intron          17666..17790
                     /gene="COL1A2"
                     /citation=[10]
                     /number=20
     exon            17791..17898
                     /gene="COL1A2"
                     /number=21
     intron          17899..18258
                     /gene="COL1A2"
                     /citation=[10]
                     /number=21
     exon            18259..18312
                     /gene="COL1A2"
                     /number=22
     intron          18313..18425
                     /gene="COL1A2"
                     /citation=[10]
                     /number=22
     exon            18426..18524
                     /gene="COL1A2"
                     /number=23
     intron          18525..19435
                     /gene="COL1A2"
                     /citation=[10]
                     /number=23
     exon            19436..19489
                     /gene="COL1A2"
                     /number=24
     intron          19490..19952
                     /gene="COL1A2"
                     /citation=[10]
                     /number=24
     exon            19953..20051
                     /gene="COL1A2"
                     /number=25
     intron          20052..20451
                     /gene="COL1A2"
                     /citation=[10]
                     /number=25
     exon            20452..20505
                     /gene="COL1A2"
                     /number=26
     intron          20506..21058
                     /gene="COL1A2"
                     /citation=[10]
                     /number=26
     exon            21059..21112
                     /gene="COL1A2"
                     /number=27
     intron          21113..21262
                     /gene="COL1A2"
                     /citation=[5]
                     /number=27
     exon            21263..21316
                     /gene="COL1A2"
                     /number=28
     intron          21317..21589
                     /gene="COL1A2"
                     /citation=[5]
                     /number=28
     exon            21590..21643
                     /gene="COL1A2"
                     /number=29
     intron          21644..22595
                     /gene="COL1A2"
                     /citation=[10]
                     /number=29
     exon            22596..22640
                     /gene="COL1A2"
                     /number=30
     intron          22641..23772
                     /gene="COL1A2"
                     /citation=[10]
                     /number=30
     exon            23773..23871
                     /gene="COL1A2"
                     /number=31
     intron          23872..25089
                     /gene="COL1A2"
                     /citation=[10]
                     /number=31
     exon            25090..25197
                     /gene="COL1A2"
                     /number=32
     intron          25198..25866
                     /gene="COL1A2"
                     /citation=[10]
                     /number=32
     exon            25867..25920
                     /gene="COL1A2"
                     /number=33
     intron          25921..26853
                     /gene="COL1A2"
                     /number=33
     exon            26854..26907
                     /gene="COL1A2"
                     /number=34
     intron          26908..27587
                     /gene="COL1A2"
                     /citation=[10]
                     /number=34
     exon            27588..27641
                     /gene="COL1A2"
                     /number=35
     intron          27642..27745
                     /gene="COL1A2"
                     /citation=[10]
                     /number=35
     exon            27746..27799
                     /gene="COL1A2"
                     /number=36
     intron          27800..27895
                     /gene="COL1A2"
                     /citation=[10]
                     /number=36
     exon            27896..28003
                     /gene="COL1A2"
                     /number=37
     intron          28004..28364
                     /gene="COL1A2"
                     /citation=[10]
                     /number=37
     exon            28365..28418
                     /gene="COL1A2"
                     /number=38
     intron          28419..29216
                     /gene="COL1A2"
                     /citation=[10]
                     /number=38
     variation       29128..29129
                     /gene="COL1A2"
                     /note="additional 38bp"
                     /citation=[10]
                     /frequency="0.6"
     exon            29217..29270
                     /gene="COL1A2"
                     /number=39
     intron          29271..30272
                     /gene="COL1A2"
                     /citation=[10]
                     /number=39
     exon            30273..30434
                     /gene="COL1A2"
                     /number=40
     intron          30435..31646
                     /gene="COL1A2"
                     /citation=[10]
                     /number=40
     repeat_region   complement(30910..31195)
                     /rpt_family="ALU"
                     /rpt_type=dispersed
     repeat_region   complement(31216..31286)
                     /rpt_family="L1"
                     /rpt_type=dispersed
     exon            31647..31754
                     /gene="COL1A2"
                     /number=41
     intron          31755..32426
                     /gene="COL1A2"
                     /citation=[10]
                     /number=41
     exon            32427..32534
                     /gene="COL1A2"
                     /number=42
     intron          32535..32919
                     /gene="COL1A2"
                     /citation=[10]
                     /number=42
     exon            32920..32973
                     /gene="COL1A2"
                     /number=43
     intron          32974..33059
                     /gene="COL1A2"
                     /citation=[10]
                     /number=43
     exon            33060..33167
                     /gene="COL1A2"
                     /number=44
     intron          33168..33307
                     /gene="COL1A2"
                     /citation=[10]
                     /number=44
     exon            33308..33361
                     /gene="COL1A2"
                     /number=45
     intron          33362..33732
                     /gene="COL1A2"
                     /citation=[10]
                     /number=45
     exon            33733..33840
                     /gene="COL1A2"
                     /number=46
     intron          33841..34315
                     /gene="COL1A2"
                     /citation=[10]
                     /number=46
     exon            34316..34369
                     /gene="COL1A2"
                     /number=47
     intron          34370..34495
                     /gene="COL1A2"
                     /citation=[10]
                     /number=47
     exon            34496..34603
                     /gene="COL1A2"
                     /number=48
     intron          34604..34935
                     /gene="COL1A2"
                     /citation=[10]
                     /number=48
     exon            34936..35194
                     /gene="COL1A2"
                     /number=49
     intron          35195..35601
                     /gene="COL1A2"
                     /citation=[10]
                     /number=49
     exon            35602..35786
                     /gene="COL1A2"
                     /number=50
     intron          35787..36497
                     /gene="COL1A2"
                     /citation=[10]
                     /number=50
     exon            36498..36740
                     /gene="COL1A2"
                     /number=51
     intron          36741..37553
                     /gene="COL1A2"
                     /citation=[10]
                     /number=51
     exon            37554..37700
                     /gene="COL1A2"
                     /number=52
     polyA_signal    37880..37884
                     /gene="COL1A2"
     polyA_signal    37975..37980
                     /gene="COL1A2"
     polyA_signal    37989..37993
                     /gene="COL1A2"
     polyA_signal    38325..38331
                     /gene="COL1A2"
     polyA_signal    38492..38497
                     /gene="COL1A2"
     polyA_signal    38513..38518
                     /gene="COL1A2"
ORIGIN      
        1 cattaccacc ctgagtcatt ttgctcagaa ttagtctctg actctcagca acacaggaca
       61 aatacacaca tatgccctgc aaaggtaatt cagcacagtg gtaacaatga ttcttagaaa
      121 tcatttctca ctcttctgat atgcagaaaa aaatttgtta tgatgtagta ttgaagtttt
      181 tctttcctga taaaaatgat ttccacttta aaagtttttt gttagttctg taacggtgat
      241 atttcaggga aatgttaaaa atgttcttgg aatatacaat tcaacctcag gtcttttgtt
      301 gttgttgttc ctagaaccta gaaaacttca aacattgttg cctagttaga aaaaaatttg
      361 aatgtggatt gctccctgta aacccccttc taggaatgac cagtaaccct ttcaaattct
      421 ttcactccca gttacttcaa aaaatcatcc aaagtggtct cccaagtgag tgcctttaat
      481 tagaataaaa caagagttta ttatagtttt tggttatcca cttttacttg cattaacctt
      541 tttttcttct tttacattta gaaagagtaa cctgctttag aatagtccct tttatttaca
      601 gaagctgctg atggagttaa cttctgcaga aattcttcct taaggcaaag caaaaaaagc
      661 ggggaggggg tggggggaag gaagggaaaa agattctcag ggaactacag cccacttgct
      721 tctgtttctt agagacagaa ctgacctaaa gatgccccct ttgcgatgac ttctgggata
      781 gagcagcact ctaactaggc ccccgctgcc tcatggggac cttaggcaag tagaggagag
      841 gcctgacaca cacacacaca cacacacaca cacacacgca cacgcgcgcg cgcgcgcaca
      901 cacacacaca cagcctttca aacctagggc ctggaatgcc atcccaagag gctttagaaa
      961 aaggcacagg acctttggcc tcccacctca gggtcaaagt accagttcct cctctcccta
     1021 gtagggagtg gagggttgga tggaggcggc cagagaagag ggaagttggg tgctggggag
     1081 agagttaaca tccacgttgg tgggcgcact gcttggggtg ttaccagcga agattacgaa
     1141 gaccccaagc tcgaatcaga agggcctctg gatgtgctag gggaggtgct tgggtgtaac
     1201 tgtaagagat gggacagaga gtaagcagca aggtcaagag ggaccggggg gctcacggga
     1261 gggttgaagg gtccaggctc agggtagaac tggtaaatcc agacaaggag cccatggaga
     1321 aggggagggg agactggaaa ccatgaaaga tcccccaccg cagcctcaga aaggagagac
     1381 tgagaaataa gttctcggtc tccaggtcgg ttggagtcgt gtcggagtgc cagaccatcc
     1441 cccaaaagac cctctttgga atgagcctca gcaaaggcaa gctaggaggt cgaaggactt
     1501 ccccaggtga ctcggtctag tctagagttc gcaaagccta tcctccctgt agccgggtgc
     1561 caagcagcct cgagcctgct ccccagccca cctgccaaca aaaggcgccc tccgactgca
     1621 acccagccct ccacagacag gacccgccct ttcccgaagt cataagacaa agagagtgca
     1681 tcactgctga aacagtgggc gcacacgagc cccaaagcta gagaaaagct ggaaggggct
     1741 gggggcgggg tgcaggggtg gaggggcggg gaggcgggct ccggctgcgc cacgctatcg
     1801 agtcttccct ccctccttct ctgccccctc cgctcccgct ggagccctcc accctacaag
     1861 tggcctacag ggcacaggtg aggcgggact ggacagctcc tgctttgatc gccggagatc
     1921 tgcaaattct gcccatgtcg gggctgcaga gcactccgac gtgtcccata gtgtttccaa
     1981 acttggaaag ggcgggggag ggcgggagga tgcggagggc ggaggtatgc agacaacgag
     2041 tcagagtttc cccttgaaag cctcaaaagt gtccacgtcc tcaaaaagaa tggaaccaat
     2101 ttaagaagcc agccccgtgg ccacgtccct tcccccattc gctccctcct ctgcgccccc
     2161 gcaggctcct cccagctgtg gctgcccggg cccccagccc cagccctccc attggtggag
     2221 gcccttttgg aggcacccta gggccaggga aacttttgcc gtataaatag ggcagatccg
     2281 ggctttatta ttttagcacc acggcagcag gaggtttcgg ctaagttgga ggtactggcc
     2341 acgactgcat gcccgcgccc gccaggtgat acctccgccg gtgacccagg ggctctgcga
     2401 cacaaggagt ctgcatgtct aagtgctaga catgctcagc tttgtggata cgcggacttt
     2461 gttgctgctt gcagtaacct tatgcctagc aacatgccaa tgtaagtgcc ttcagcttgt
     2521 ttgggggaga ctgggtagag aggttagatg ggagggcacc ctgccctgaa aaggaaaacc
     2581 tgtaacctga attccaggta cacttggagg gcagactctc aggcatgtgg gaaaacgccg
     2641 gaattgataa gaaacatgga aattacttta aaaaatgaaa acataaaagc cttgccaaaa
     2701 gttagggaac ttttcctcta agttcagagt gagacagtta actcggtctg gctcctcagc
     2761 ttagtaaccc ccaaagggag cggaaggtct ttttccctaa ggatgagata ttaacgacca
     2821 atgtggtgga ggaagtcaag ggcctgcacc ccacaggccc cataaccgca ctgatgtcca
     2881 ccttgtaaaa cttgaggcct gcgttagaaa gcccttcaac tgagtaatgt aaaactcacc
     2941 tcctaagagc ttttatcttc tgggcattgt aaggcttgtc cggaggagga ggatgacgat
     3001 gctgatatga tgatggttat aaggcgccct ctggaggaag gaaaatgaaa gtacagggga
     3061 cagggcctta agcagatgga atcccaatta aagcttctac ggatttatac agattaatga
     3121 tcagcatttc tggttggagc ctttcccagt ggctagtcag tgaaccctgg aaagaagaat
     3181 ggatgctact tggagtgggt acattctgaa aagtaatata agtgtctcaa ttcactttct
     3241 agtcatggaa atggtaacat tttttaactc aaatctgctc taaattttgt ttgagcctga
     3301 gaattacccc tttgacatgt tcccagtgat aagcaaacat tatgaacgca gcaagttgag
     3361 aaatatcaac attgagatga gactcaagag accggggttt ttcccatgag tctgacacca
     3421 atttgctgcg tgactttggg caagtcaaac ggccttttct aaaatgtgag acagagatta
     3481 aagggacccc aaggccactt tccagctcta ggttccatgg ccagactttc atgtcaacag
     3541 agaatgaaga agatcagtcc gttttcatct tgaaaatggc tgccaaagtg ctagacaaag
     3601 atattgacta gatgggggat ggtattgtct gaccacaccc agtactccaa aaagttgttc
     3661 cacccacaca gcacggtgtc taccactgca taatttctaa tgcatttgtg tgcttgtgtg
     3721 tgtgtgtgtg tgtgtgtgtc tgtgtgtctg tgtgtctctt cccccttcat tcacttttag
     3781 tatacatact gtggatacta aggagtaatt gcagtgaaca aattcacatt accgagttca
     3841 tatttttaat gagatcttga gagtgggagg aaagagtcgg ctcctagaga ataaaatgaa
     3901 ggcagactta gggaaatttg aaggtacaaa ggcaacttac cttctgatca acagccaacc
     3961 acagtctgga ataaatgtta tcaaacacac attcttcaaa atggtccgtg tctgagtaat
     4021 taaaaggcaa atttccaaaa tcataaggac ttccgttaat caagtcaggc ataattattc
     4081 ttcctactga tgacacaatg aagtaaacat atcattcttg taatttaaca gtaattctcg
     4141 taaattgccc ttaaatgtca gtgctggatg tggtccaccc tcctaaattg tgactgttgc
     4201 aacagatgtt ctcacttcaa ataacgcact tcttggccac ctaattaaag caatttttgg
     4261 ggtgattcat cctactgcaa gcttggccac acttgtatcc tgtattaacc tataattttt
     4321 gtaccgtagg agaagaattc actctttaag gacttataac aattatggca aaagggggga
     4381 tagtactttt gtttattttt tctattattt ttcaagatct ttaatccggt ttttccattt
     4441 atacaaaact ctttctccga gacaaaaatg atacatattg gtaaaatgat cttacctaat
     4501 ttaagtgaac taatttaaag caaaattcag atgtctgaat taatccattt tcatagttaa
     4561 taatgtgcaa attagacctt ttggaaaaag gatattaaga atggtacaaa ctcaatgaag
     4621 tactaggtaa cttcaatgtt ttataaaaaa gtaagtcagc ttcaatgttt cataaaaaac
     4681 aaattcaata tagaatttta aggtaacata ctttcctaaa ttttaccttt tttcgatatt
     4741 taggtattaa aaatgatcaa aatcataaat tatttcctca tcaatttact agtcttacat
     4801 tcagcgattc atctgtgcac tttaccagct taattgctaa gcattcaaaa tatccttcag
     4861 acacattaat atttcacaac agttataaaa tagtaaataa ttaataattt aattcaaaat
     4921 acatttacat attaatattg caaacaaatc accctgctga tccctgccat acttttgacc
     4981 tgcataattt ctaggtcatt aaaatattct taaaaaaata taattggtcc ttaattaggt
     5041 aattcaattc tataaacttg tttctctatt tgttaattat tgctattgat ccatgaagtg
     5101 atactaataa ttgtttccta ctttttcttt tttttttcta cagctttaca agaggtgagt
     5161 aaaacttttt ttagaatttt taaaaatact ttgattccct tggctacagt gatgtcttct
     5221 cttggaaggg aagaagttac attaatattg accatcctag attaaaacct ttctggctgc
     5281 cttagaaagt acccacccaa ttttccaaaa taggcggggc tactgaataa gactaggttt
     5341 ataaaatatt cataagaaat atagagtaaa taatccaata gaagtttgag ttttaggatc
     5401 agcttctatg aagcagaaga tttcactgag ctagagaatc ttttcactcc tttggaatta
     5461 tttgcaaaag cacttattgt taacacattc ttagctcatg agttgaattt gaggcataag
     5521 tacaggtacg tattgctatg tatttttgtt ctgtaggtac atatttttat ttgacatgtt
     5581 ggtaaaattt taaattgtag tttgaaatat taaactgaga taatagtaaa tgcataatgt
     5641 aatgaattgt gaaggtatat ttgtatacta caccaaaatg gaagctgttt ttaaatatat
     5701 atatacaatt ttcttcataa taatctttga tttattcttt tctaggaaac tgtaagaaag
     5761 gtaagagtac actacttctc cataaatatc taaaattatc agggataaca taatttaact
     5821 aaatttatag tagactatag aaggaaaata ctttatcaaa attttgttca tatgaatata
     5881 cattagctaa agcataaaat aaagtagctt tgatgtttaa gataacaaag tttaattatc
     5941 ttctggaatc atctgtaatt acatttatgt gatacaaact ggtgatttac atacaaaagg
     6001 aaaaaaaaag acttgttttt attctggaga tggaaggcat attatgttaa ttatagggag
     6061 taaaaaaagt ttattttaaa gggtttgact atataaatgt gctgttaaaa atgtaacaaa
     6121 atgatcattt aatctacagt tatcatctta ttcaaaatgc tatgcatagt attgtcctaa
     6181 tagctgaaga ctatagcagc ttccaatcct ccagctgaaa aaaaattacg tataattaca
     6241 attaaaatat atactttatc tattgcattg tgtcaatttt ttatatgcta tctaataaca
     6301 ttgtagttac atcagtctta ccaactaatt attatcaaga atgatttgtt tgttcactgg
     6361 aaattacttc ttaggcattt attattgtcc tgtttgtatc tttcctgtag ggcccagccg
     6421 gagatagagg accacgtgga gaaagggtgt gtaatttttg aactataaag ggcttcgtcc
     6481 cgtatttgaa taactatatg ttagaaacta caggaactgg caatttataa gaatattatg
     6541 tatccagata attgtacacc cctttaaaca ggtaatgcac tgcagaagaa gcgaatgagc
     6601 attattatat atgatcaata tttgttttag gtcaaaatta ccgttaaaaa agaaaaactg
     6661 ttacagtcat attctttgca tggtctactt tctttatttg taattgaccc atccaacaca
     6721 tgcataatgg aaatatatct acctaccacc acagtcctct ttttaacaca tttcatttgc
     6781 ttttgaacta agatccctta ggtagcttgg aaataatagt gaattagtag tcagtaacat
     6841 gtttctctgc tcaaattcat gcatgtacaa gtcaggctta cattttattt gtggcattct
     6901 taaatctccc tgctatgctt atttgacatt tataactatg tggttttgca ttgtataaca
     6961 cttttgccaa tatatgaata cctatatctt atatctatta ggaagaggag acttacatgt
     7021 atttcactca atttattaga aatagaatta aatcagttaa ttattttaac aatacaagta
     7081 gttaatgata gtaaatctgc aggattttct ctcctatgat aaagtgacct tattaactgt
     7141 cacatcagtt aattcattca catgtaacat accaaaacaa ttgaatcagt ttgtcacagt
     7201 cagagatcgg caataaaaat acgatgtaag tccttgtgca ctgttaaaca tatgaagcac
     7261 gtggaaccat acattttggc tataattttt atatttgaat actggagctt cagtatgaat
     7321 taatattcaa tggccgagat agttctttag gaaaactacc ctgtgatatc ttaagagtta
     7381 ttaaccctct ttctaaaata gactcataag tgaatttcaa tcaatgacaa atatagtata
     7441 ttaaatttcc accctacttg cacatagaaa ggtctgaaca actgatctta ccacatataa
     7501 ttcttaggtt tctacagggc ctgtctaacc tgaccttact cactttttac ataacagggt
     7561 ccaccaggcc ccccaggcag agatggtgaa gatggtccca caggccctcc tggtccacct
     7621 ggtcctcctg gcccccctgg tctcggtggg gtaaggtgtc ttacgtattg ctaactttta
     7681 gctaacttca gttgaaagaa ggtttattgt ggaatttatt tttagcagtt aagggataat
     7741 tcttccattt gaaaattagt atattttatt tcatttattt ggttttttca ctcaagattc
     7801 tgctttaccc attctctttg tgagcccttg tcaattacag gactggtctt tgtgtgcact
     7861 gaagttagct gtggccatca ttaccattat ttaatttgga gatttaatat cttttattag
     7921 taaggcacaa ataagaggtg ttgcattatt aaggattttg attagattga actgtgtaag
     7981 tgaaatccct gatcttaagc aattttacaa acatcctacg ctttttattc tccttgactt
     8041 gaagtctgct gaaccaacat tcaaagcggt tttaggttta atttgcttga aactaatttg
     8101 agaaaagtac atttcccttt ttcattaata tcttctttta gcttcatgtc tttaacaatg
     8161 gtatgagtgc caaatgacct cactgcagga aggaaaacat atttgcttaa ttggttagca
     8221 ctatgaatca gaagcctgat tctaataccc aactgtatgt cagtaaaata agacctttct
     8281 cccccaaaga tcttattatg attgcttatc tatgaattgc attaaaaagc agcttcttta
     8341 atagagctac cactataaga gagatcttta acagtaaagt tattactgtg aactagtttt
     8401 tagaagtttt atcttccaag gggtatttta atttaatttt cctctaaact tgaaaactct
     8461 ttatgccctt cctgaaactc cagcaagaaa aagatctctt agtcattttg tgtagctccg
     8521 gtggggaagg gcaacaggtg aaaatgtgaa gatgtcctct tgagctctgt ctaatttgtc
     8581 aggagccctt agtaacatta aaagtttaga aagcttccct tcctcagagt agaggtaaaa
     8641 ggtgggagtg gagacaccga gttaaggcag aggaagggct caaaaagtaa agtagggaag
     8701 ttctccattt caaagaggtg tcggccaagt ttttgacgta cagctctcat aactttttag
     8761 gaatttagtt caatatagaa ttttaaacta ataattatat caaaaacatt gccctctttt
     8821 aaataacaac agaaaaatat ttacaagtag aatgagaaaa tgaactacat gactagtaac
     8881 taaaaatatt ttatatatat atataatttt ttttttttac ttctctagaa ctttgctgct
     8941 cagtatgatg gaaaaggagt tggacttggc cctggaccaa tggtatgctt atctgtttat
     9001 cttagccaaa aaaattgcta aataaatcat tcattttatg tcacatttta ccacgccatt
     9061 tatttagcta cctaagttaa cactcaatac ttagattata taaaaacaac tctttttgtt
     9121 ttcaaattta tgaaaacata agttaaggag ttcacttttc tttacaaaag aaagattaat
     9181 tgatctttta tgattatatg atctttttga ttatatgatc ctcattaaga tagatcatat
     9241 acttatgtcc aagaaataat ctttggacat agtaaccata acttgggcaa atcaatttaa
     9301 tttaaaacag taatcactct gattaatttt ttaatattct ttaacattgc ttagaatttt
     9361 aagcaacact tagaggcata gaactattta ttaagttctc tgaacttgtt ggaaaggatc
     9421 aacaagttct atctagtcca gctaactcat tttaaaatgg gagagtttaa gcccttttct
     9481 caaagtcatc caggtaacta atgacataac tagaactaga tgccaggcaa gatgtctaat
     9541 atttgcttac atcatggttt atgtacctag tccttgaata aaccactcat ttagtcaaca
     9601 gatattaatc agatgccttc aatgggccct aaactgtatt aggaactggg gaaattacaa
     9661 ggaatatgac agattctgat ccttcctcaa ggagttaaca atataggaaa tgtttctttt
     9721 tctgaatttt gaccaaaaaa atcctttttt agtctattga ttgtaaatct atatagaaga
     9781 gagtatgagt aaaaatctag catttatgtc actcagtaca aatattcagc accataccct
     9841 atcagtggag caccgcttag aaacattccc tatatgatga tgatgatgat gatgactatt
     9901 aacaaatgaa gcttctaaca agcattagag agaagtttga agggaaaaat gctaatacga
     9961 gcatgcaaaa tgtatactag catatatgaa atagagggga aaactgccag aagtcaaagt
    10021 gttaggttga ttaagcacta cagaatttaa tgtatacaca cacacgcaat ttagtgattt
    10081 taattaattg tttcaaaaca aaggtattta tctgcccaaa gtcaacaagg tctttaaaat
    10141 gtaaatttta cctgagcagt gcacttagtg ctctatcttc aaaagaagat gttctgctgg
    10201 agctaatggc ccacagtaag ctaatatact ctaagggtga gataatattt tctgtaaatt
    10261 aaaactccca cttgagaaat aatgtacctt taattgacga cttctaattc cctaattttt
    10321 tctggtagtt taaaatgttc atatctgaaa tgaaaaagta gagtgtttct tttggctttg
    10381 tttatattgg atttttgaaa ttagctgttt cagctaatgc tggacattag tcagttttaa
    10441 agcagtacct acatctcaag aagaagcaag ggggcggaaa gtaaagagct actaaatgtc
    10501 atttttaaaa agcccactaa gctgggaaaa ttaatatgga tttcagatac ccctgttttc
    10561 ggaacatctg tcttggcata aagcagagta ttttactttg aaatatcagt gaaatataat
    10621 ttaagcttgc acatccacac acatgcacag acatatgtaa tcaacagata tctgtttcac
    10681 aaatagggaa gataggcagc aataaagtat taaaataatt tccatgttgg aaaatcaata
    10741 actataaaac cccacagggt tcttctctga attaatgagt aatcacagcc tccatgaaat
    10801 acactacatt ttatgtaaat gaaattgttg caaatacatg aaaaaataaa tataattaga
    10861 aattcatgat gtcaaagaaa attatttttt aatgtatgcc taaaaagcta ttgtgatgga
    10921 aaagtgacag tttcttttaa tgtcagagca atttctaaaa ccaaatgaat aattcttata
    10981 attaaaatga cgtacatttt agataaaatc catgttattt cactctaggc attaatacag
    11041 taaggtaggt ttgactgcag agtccccaca gctgatgtca cgaacaaatt acttgagact
    11101 ggtacatgaa atattttcag cattatgagg aacagaccct acggatgagc ttacacaggc
    11161 attgattact gcaaagagga gtcaagaaag tgtatttagc ttacaaacta ttaacagccc
    11221 tgttttaccc tacttttgtg ctatggaaac aacaaagggg aaaacaatct tccatcattt
    11281 gggccatatt ttcaacaata atatcatata atagactctt ccagaaggct gtttcaataa
    11341 tgttttattt ttccttcacc cctcattaca tccacttttg tttgacattt tcatcagtca
    11401 ccaataaccc ttagaggagc gataaggtta taacaaactt ctctctaatc attaagaagg
    11461 acttttgatt cttttcaatt tatgtccttt gtggcaataa aaataccaat ttcttagcta
    11521 aatatgacat aggaagatga catatgatca aagatatcca aatggacatg cttcatctgc
    11581 tgtatagaag acaattgtat attctgcact tctgcaaaga ctgattcact tcattgcatc
    11641 agaacaatct caatatgccc aattgtgcac aactttaagg aacctatctg ccccgtctaa
    11701 ttctcattga tttctgttga tatggattgg gagaaaagga aaagcaaagg gagagaacta
    11761 gtgcaggaag tttgagtcct taaattcttc cttgggagga ataaaaacta tggaatcaaa
    11821 ccacaacaat ggcactgcta agttggtcat gtctgacccc agccaacacc atgacaactt
    11881 atcagtgcta actgttgata tatctgcttt ctttacaggg cttaatggga cctagaggcc
    11941 cacctggtgc agctggagcc ccagtaagta ctgaaagctt gtaatgcctc ttatgtaaaa
    12001 agacagagaa ttaagaaata aaggcttgga gtatgacatt ctttttttct tttagggccc
    12061 tcaaggtttc caaggacctg ctggtgagcc tggtgaacct ggtcaaactg tgagtacatt
    12121 tttccacctt tgtgataagt ttttttccag gaagtttatg aatataacct tagtgaaatg
    12181 atgggtctcc cattttctta gggtcctgca ggtgctcgtg gtccagctgg ccctcctggc
    12241 aaggctggtg aagatgtaag tatttactct taagcacttt caaaatgcta tttaaatact
    12301 cttgcctcaa caagattttc tagattcaaa ttaagtattc tgccaaaagc tgaatatgcc
    12361 tgacagaact cttaatgtat gggaaatatt attttaatga aatattaact aacctacttg
    12421 tattaaggga aagattaaat atatatctgg atccatattt ttatgtgata actttctccc
    12481 cttttgtaaa aaccaagatt cccccatttt gtctgatagt ttaccaagaa gaagttgact
    12541 ctacaatgtt ttcatgttta gggtcaccct ggaaaacccg gacgacctgg tgagagagga
    12601 gttgttggac cacaggtgag actttttaca ttggtagata gcacaaacat cataggccta
    12661 taagatagtt gctaaaacta gcatcaatct aaatgacaac atagatgtca cccaaactca
    12721 taacatgaat cgaaggcatc taataaagaa aaaagcctag ttaaaaaaaa atgcatatac
    12781 attttattca tgcaaataat ggaatataaa tgacagcaag cataccataa gcaactaaat
    12841 tgtgttttct acaaataccg tattattagt tactcacatt agagcaagtt aatttgtcgc
    12901 tctgtgctta gaggtatact agactttggt tcaaagcttg aactttgatg agaataaata
    12961 ctttggaggg aagaagtcac tgtcttttta tttatggtaa aacattattc accatcttct
    13021 gtatttcttt ctaagggtgc tcgtggtttc cctggaactc ctggacttcc tggcttcaaa
    13081 ggcattaggg tgagcacatt ctttactcag aagagagaaa atgcctatta atttttggaa
    13141 aaaactcaag tatgtttaaa atcttgggtg acatatactc actttcaaat ccctggagtt
    13201 tgccaaaggg aagaaagagt taaagagtca gatttcttga aagtaaagtg gggtgcaatt
    13261 ttttcagtct gttcatagct accaaaaaac aggctcacta cagagaaaat tatatagaac
    13321 atgtattact tattgagtat ttacaaccgt ctgaaaatca taaaattatt aaggatggaa
    13381 aagatgtgag agaacaccta gtcctccatc cttctctctc aatggcaaga aagttaagtg
    13441 acctatctag ggcaatagac tgagtttgct gggacctgga acactggact tctttctact
    13501 gcagcagaca agacttaccc aagagagatt aatggcaaag atatacaata caatttttat
    13561 ttgaccaaac actatcatgg aacagcattt tataataagg ctttcctttc agggacacaa
    13621 tggtctggat ggattgaagg gacagcccgg tgctcctggt gtgaaggtaa atattaaatt
    13681 agaagcactg tttttaagca cttgattgaa attccccatg acctccaaaa aagtatatta
    13741 tactgaagac tacccatatt acaaaaagta tttttatttt ttttctttcc tgtacttcaa
    13801 atccctcaag gatggggact atgagagtct gtgaaaaaag gtcaattatt aatatttatt
    13861 aaaattcaat atctattaaa caattgagat aaaaataata ttaatagttt cttgttccat
    13921 ttcctttcct ccctctataa ttccagtgta tctctgcagc caaaataaaa gtaaataaac
    13981 atataatcag agattacgac actctgtatt attttaaact gtaaattctc ctttgccaca
    14041 cactaattag ataggtacat tcatgtcgct atacactttt caacctcttt cctgtgattt
    14101 atctgtgcac actcaaaaaa attttaatta ggtaattaaa gtctcagaag tgtgttatct
    14161 cttggctagg ctcttctctg acagcgtttt caactataaa atgttctctt tcctattaag
    14221 gagataatgt gatattaaag tgaataccaa cgtaattaca aattaatgag taacgaatac
    14281 tagcgggacc agaaatgaac atgaatatgg agaatctatt ctaactttcc agctgccaca
    14341 caaatggata aggtcaaact cattctccca agagcccgat ataacagctc agactactaa
    14401 tcactgtatc cataaaatgt tagagctgca aggagctttg gagaccccct cattttgcag
    14461 aggtgggaaa ctgaggcttc gtgagagcaa ttgacttgcc caaagtcaca catctagagg
    14521 ttagaaagtc ataggctaga aatgatcccc ccttgccact tcaatgctta ttcccaaaga
    14581 atagacttca catagaatcc tggaaattaa gggtccttat gaggtctctt aaaccatatt
    14641 tcccctatat ctaaatcaga ttatctttaa aaaaagttct tttacatgtg ccatagtatt
    14701 aaatcccact actactacta ctactactac taccctggtt tttactcagg ataagaatat
    14761 agattggaaa taaatatgat ggctctaaaa aataccatga agcttcaatt tttcatgcac
    14821 attttatgaa agtgataaca ctgagtgttc aaaataactt taaaaaggat aaatatggtt
    14881 acattgaaag caaatttatc ctttgccatc tctttttatg atattgtttc tagtatataa
    14941 ttgatatcct gaatctaagg gagaaattgg ggaggaggta cactcaaata accacatctc
    15001 cttagaacct ggatatgtgg tactatctga ataaaaactc atgttagcac attttaaaat
    15061 ctgtgtgtct ggcataattg aaaaacaatc tatatgtgta agaaatatta tgaagtatat
    15121 gaatggttca aagtaaaaaa aatagagtaa aattgcacta tcaggaaaaa taattgttat
    15181 atttaatgaa caaaaactca atccttctcc atgtagggtg aacctggtgc ccctggtgaa
    15241 aatggaactc caggtcaaac agtaagtatt gactacttca ttgtaaattt aaatgtgtac
    15301 actctttatg agatggaact tctttaatgt ttttgctaat cactgtatcc ttcagcattg
    15361 tattctttga tgtttttcta atagccttct gatacttaat tgaaatccac tactgtttag
    15421 ttggaattag aaggcaactt atttattttt agtgtattct tgtacaggtt ggaaactgaa
    15481 caaagcaaat gatgcctgtg acttttttta aattagcatt ctggatttta ttgaaaatat
    15541 ttctgcttct agggagcccg tgggcttcct ggtgagagag gacgtgttgg tgcccctggc
    15601 ccagctgtaa gtgcttccat ttttgttcag tttcatcctt ttaaaaaatc ttctaatggc
    15661 tgtcatttaa gtttccacct gatcttccct ttattttctt cttagggtgc ccgtggcagt
    15721 gatggaagtg tgggtcccgt gggtcctgct gtaagttttg acactgggga gtttgaaagg
    15781 agttgagaat gtggggtggg tgctgtcttc ttcattaatc tcttacgaaa tagcatcatt
    15841 tcagacactt taccaaatgt tctgtgaggt cttttgaagg ctccatttat aagtagtgta
    15901 agccatttat aagtacctga acttttgatt gatgtataaa gcaaaatatc cccaccctgg
    15961 ataccatgaa tgtcttgcct ttgatgagat cctaacgaca acagactggt tgtcagtttt
    16021 tttctttact aatataaaca gtgtcatgcc actgtaagca acttcaatct tctgccattg
    16081 ttattgtttt cttaatttac ttggaggaaa tttcttacca ccttctgctt tgatttcagg
    16141 gtcccattgg gtctgctggc cctccaggct tcccaggtgc ccctggcccc aaggtaaaaa
    16201 cactggtgac cattgtcact actttgataa actttttact gtgatgtgaa agattggaac
    16261 tgtgtttgca gataaagaga taattacgaa acagttacct taattattcc ttcccttcaa
    16321 aatggacata gaatgaccag ttttctcact ctacatttga aatagatcat ttctctgcac
    16381 tgtgcactgt gcccatcgat atagatgaca acatggaaat tgtctctagg actagttagt
    16441 taggactgac tgagaaccag agtcaaccac agagagacag aaggagaggg aaggtagtaa
    16501 cagtagccaa gatggcagaa tcaagcaagg aaaataggaa accaaactca aatcttgtaa
    16561 taaaacggat aagaaaaata attgcaattt tgaagtttta tgaagacatt tcataaaact
    16621 tggcatctta aaaacagata tgctgtttca ttatttgctg gttaattcct tggtttaatt
    16681 tcctctttta gggtgaaatt ggagctattg gtaacgctgg tcctgctggt cccgccggtc
    16741 cccgtggtga agtgggtctt ccaggcctct ccggccccgt tggacctcct gtaagtagcc
    16801 actgtcttta aactttattg agtaaaagaa aacaaaggtg gagtatgggg aagaagaaga
    16861 atgaagatgg ggtcaaagaa gaaccgaaat attccaatta actgatatcc ttctcctttc
    16921 cttttcctca tagggtaatc ctggagcaaa cggccttact ggtgccaagg gtgctgctgt
    16981 gagtatacct gtgtagctaa aatgtgctgc tatgatttta aaggcattta atgtgtgctg
    17041 cctctacagc ccatcacctc cctaatggac cacactgcat tttccttcat agggccttcc
    17101 cggcgttgct ggggctcccg gcctccctgg accccgcggt attcctggcc ctgttggtgc
    17161 tgccggtgct actggtgcca gaggacttgt tgtaagtggt catgactgtg gttctcatca
    17221 tcctgaaata ccacctctgc catcatttca tcactatcta gacttccact tgtagtttta
    17281 ttattcctat ttttctcttc cttagcattt ttagtttata tttcttatat atatatgtac
    17341 actcccgtct gctatatgca cacagacatg cccttcctgt tatcttaaat cattacctca
    17401 aggtaaatga ggcaaagttc tacaatatca gttttgtccc ttcgaccaat aataccattc
    17461 ccctgtactc aatttaaata tgaacagggt acatttccta gagaacttga gcttctcttt
    17521 accttgaccc acaaatattc taagagattt gtctgcaaga gagtttcaac aaatgtttgt
    17581 cctttgacca ctgttctgta ttgaacccta gggtgagcct ggtccagctg gctccaaagg
    17641 agagagcggt aacaagggtg agcccgtaag tagctctatc atcacacttt tataaagtta
    17701 attgtttttc tcattccagt ttctccagct ggacatagta ttaaaattat tttttttact
    17761 ccctcttctt ttgttctttt cattaaacag ggctctgctg ggccccaagg tcctcctggt
    17821 cccagtggtg aagaaggaaa gagaggccct aatggggaag ctggatctgc cggccctcca
    17881 ggacctcctg ggctgagagt aggtttcaaa tgctcccaac accctaacac accagaggca
    17941 gattatgata ccccttcatt gggaattggt caaaattact gactgtgttt tcttaggcaa
    18001 aaaaagcatc tgctttccat ctgccttatt aaatcagtga ctctcaattt aatatgttat
    18061 aaaattggcc tggaaacaat gttgacctac ttttgcagga tgctcatcta tgaattcctc
    18121 taggggttgg gtgaagtgtt ttggcttggt ttgtgtctgt atctcccctg taagagatca
    18181 tgctattttt aacaaactct accttatcaa agccaagaga tttctttaat tctctctatt
    18241 tcatgtactt tcttgcaggg tagtcctggt tctcgtggtc ttcctggagc tgatggcaga
    18301 gctggcgtca tggtaagctg tctatcactt acttcctaga aaggggcttg ctgcttctgg
    18361 tggtgggtgt gtcattagct ttagcatcct cctcctctat ctgttttttt tttttttttg
    18421 aatagggccc tcctggtagt cgtggtgcaa gtggccctgc tggagtccga ggacctaatg
    18481 gagatgctgg tcgccctggg gagcctggtc tcatgggacc cagagtaagt ttcaaactga
    18541 ttctgagcaa atcacacctg gcattacttc cttctttaaa gggttggtta atattgaaga
    18601 taacaataaa aacatcaaaa gtaaatttgt tagtagtctt gctgacagtt gcatttttga
    18661 ctttatcaaa gctcagtaga tattttcatg catttaatta gttcataaat tttctattta
    18721 ttacttgata caatggctat gaggtttttg gaagaataga tctattttaa tatatccaaa
    18781 ttagattggt cctcctatca gcatgaatct tttatcttaa tttgtgagtt ttatataagg
    18841 tgttcatgaa atatattagg actatacatt tttcgtttat tagattcata agtgaagtct
    18901 ttttcctagc aatcacaaag tgctgtaatg tattcagcat cacactagct atggagaaat
    18961 aacctctagg tccatagaca cactaatcca tagcaataga gtaatttttt tgcctccatt
    19021 acctcttatg ggtgaatatc aactgtaatt gtaccacaaa caagtaatag ggacaccaaa
    19081 tatagcaata agaaatccac tttggaaatt gtttactaaa agtattagtt tttctattat
    19141 gaggtaaata acgtgataca ttttgcccat atacatgttg cttaacagtt tcttgagata
    19201 tctataaaag gatgagttgc actaaatttc aataaaagga aagccacaaa aaaatagaag
    19261 aaaaatttca gaactctttt cacacttccc agctagtggc taatattcct aatgatttac
    19321 cctaggcaac aaacaaaaag tcgggggaaa aggtgccttt gttagacttc agttaatcta
    19381 aggcttgagt atgtaagtta aagtgccaat ataaaaacat cctcattatt tatagggtct
    19441 tcctggttcc cctggaaata tcggccccgc tggaaaagaa ggtcctgtcg taagtattgc
    19501 tcattttccc attatatttt caaggacact tattgcaccc ttatcaagtc tattttgtgg
    19561 cttatttata catgaacaca ttgaaaataa atatcagaca catacatcat ctgggaatgc
    19621 agagtaatag attgtaatta tggagtccaa atgaatacag gactgaaagc agagcagggg
    19681 agagaaaaac atggcaggga aaattgaagc aggtgacaag gggatgcaag agaagggaat
    19741 gagggaaatt gcatacatac gagattgaat tggctatgtg tgtactgaca tcctagttag
    19801 aaaaggaaaa tggattcata atttattaac gctttataca agaagctcta tgcattcaga
    19861 aaactattct gtttcatccg tggcagcatc ataagcttga ggttgtgaga atatgttgac
    19921 actgagtaaa cttgaaataa ctctgctttc agggcctccc tggcatcgac ggcaggcctg
    19981 gcccaattgg ccccgttgga gcaagaggag agcctggcaa cattggattc cctggaccca
    20041 aaggccccac tgtaagaatc accacaactt tcttaccctc agcactttct gtagccaaat
    20101 tttaccaaac tctagtattt atctcctgcg aatcagtcca gtctcaggga gtttcctttc
    20161 aacacaggaa aactgcaggc cacttatcac attaaaagtt tacctctagt gtatccttat
    20221 atccctgcta aaaatccatc tcctgagccc catgcttcca cagacacagg gacatcttac
    20281 tgtacatgga gctgcatggt gatggatcat ccttagataa cagaaaccac agactaggga
    20341 tctcaaaaga acacaaaaac aagcaggatt caacattgca aaatcaccgt ggttaatttg
    20401 acattaaatg tgcaaagctg ttctttgttt tgtttttcat ttttactcta gggtgaccct
    20461 ggcaaaaacg gtgataaagg tcatgctggt cttgctggtg ctcgggtagg tgctaacttg
    20521 tgtacagatc tattcacata gcattcatct aagaaccaca cttttttttt tacaccatct
    20581 gatatcattt tgtcactttc ttttcaagat ggcatcccca ggggtccttt tactatcata
    20641 aaatgccttt ttaaaaacca aacttataaa acagtgagca aaaacaaatc agaatataca
    20701 ttaggtcaaa aaatacagaa gcacttggct tttattttat tcattttgta attaaaaggg
    20761 tatgaatatg tagtagcatt ctctggcctt tataaattgc cttgtgtcgc atacttcgct
    20821 tgagtcatat caaaagttag taggcaaacc cataaatata tatacctact atgtacccac
    20881 acaaattaaa aatttaaaaa gttagtaggc agtatttggg ctttcgtggg aacccacaat
    20941 gagtttaatt catgctaaaa tgacaaactt gttttaagga agtaatacct gaggctttga
    21001 gacatcttaa actacctgct tgcagctaac catcagcctt tctgttaaat atttttaggg
    21061 tgctccaggt cctgatggaa acaatggtgc tcagggacct cctggaccac aggtgagtat
    21121 ttctcccact cttgtgctct tctgcactag aatgtatata gtcctcaaac tggccatctc
    21181 cattttcagt ccaaaagtta tacagctaga caacagtggt gacatacgtt gctatttatg
    21241 ctctctttcc tgtcactttc agggtgttca aggtggaaaa ggtgaacagg gtcccgctgg
    21301 tcctccaggc ttccaggtaa gtcaactcaa gcatatacaa tactgccttt ggtcagccta
    21361 ttgagctgta aatcaccata ccgtacctct cttctccacc acaataacat gatttcagga
    21421 ctgaagcaaa gaaaggtgca tttttttcaa acaaactttt gtgtaatgct taataacata
    21481 caatcgtgct catgttgata tttggtagcc accaccccca aactcaatta ttagcaaatc
    21541 tcctgaacgt agccatggga ttgagatttg tatttctttt catttttagg gtctgcctgg
    21601 cccctcaggt cccgctggtg aagttggcaa accaggagaa agggtgagta aaacaagtaa
    21661 tagtaagtag taactactaa acttgagaat ttccccctgt ttaatacccc actgctatgc
    21721 aattataata tgtaaaagaa aatttcgtat ttcatatgtt aatgatagtg ttttacatac
    21781 tttggtgctg atggagagaa tgagccaaat tactttagtt ctgattactt tgttttacag
    21841 atttaatgaa acatcacctt atgaaagtaa aatctatcaa tgaatatttt atttaatagc
    21901 cttacttttt gtattgttct tgataacgtt aagatacaaa ttatttcctt ccccatagtg
    21961 aaaaagtaaa tgcacaattt tcaatcaaac tagatcccga aaaattcctt ttgtgttttt
    22021 cttggcattc agacatgaca ctactataca caatcagggc atgagttctg agtcattttc
    22081 tctctaattg tgatgaatgt gcccctattt agttacattc tgtggcctgg tctcctttgt
    22141 caacagtagg acatattaag gagacagctg gtcagtaata aaaagagata cacttgggta
    22201 tacaattaac taggcaatgt acagaatatg ataatttctc ttaagaagac gatctgttat
    22261 acagctaaaa ataggcaacg tctaatattc attattattt atcttattat tgaaggaaat
    22321 agtctgtcac tttttaaaaa gcaataaact aaataatggg aaacaaattt tttgatacca
    22381 agttctggga tggatacatt tttgtcgacc aataaaattc tctctttctg tatctttcca
    22441 tactaaaagt tgttcttatt agcctgtgta cttatgcact catgtagata ctgccaggtt
    22501 tatttcactc tttccaaatt tttcaaatat tttaatcata agtgaattta cagatcacac
    22561 acagatttca tgctttattc tcatgttttg tctagggtct ccatggtgag tttggtctcc
    22621 ctggtcctgc tggtccaaga gtaagtgtta cttcattaac tttcataaac tctggcaatg
    22681 tgtttttaaa agtagtagtg ctttctcctt aaagccactg atgaccctgc aacaagtctc
    22741 tgatgctctt ctatagtcaa atgtaatctg tagaaagcat tagatttcta agttgataga
    22801 gaattttttg tttcatggct catatttcct attcaataat tacatagtta taagaaacac
    22861 ataaatcaat atatattata gtcagtgatt tatatagaca actatgctac atttgtgaca
    22921 gtggctcaac ttgagctagg aaaaataata tgttactaag atataaagtt aattttggcc
    22981 atgtgtgttg atgttcaaag cctaaagccg aacttatgag tagtcatata aagaaaaaaa
    23041 aacttagttt ctctatgggt attagcatca ctgaaatgat taatttgccc tgaaagtatt
    23101 ccatcatgtc actagttaac acatatgtag gaagctcaaa gaacccaact tataacaagg
    23161 tcctttgaaa cagttacaac gtggacctat gtgataaata ttttgggcta tagaatgcta
    23221 tgctctagtg atatttagat gtaaattgga gatatttaga tagacagaca tatatatata
    23281 tacacaaata catatatcaa atatacatat gaatattgta actgttatat cattattaca
    23341 cagggttata aaaagggggc atagatagga gaatatctaa tgttatctac acctgccatt
    23401 gctattcaac taaaatgaca caatcttttc tttgaatact acacataact ggcatctgtt
    23461 tttacctatg gatttatcac agaaaagact cctcaaagaa ggggaatgaa ttgcaaaaat
    23521 tgaatattat actctagaag caacgaattc tggagtcgta gtcatggaac attagagcta
    23581 agtgacactt tagagaatat ctcatcaatc tcttcatttt actagtggag aaattaggaa
    23641 caaaagaaat tttaatttgc taataaatgc aaaccagggc tcggaagcta cacaaatgta
    23701 aactctcata tgtaaaacag tatcactgaa agtgatgaat ggtgcaacac ttcttctaat
    23761 cacttttttc agggggaacg cggtccccca ggtgagagtg gtgctgccgg tcctactggt
    23821 cctattggaa gccgaggtcc ttctggaccc ccagggcctg atggaaacaa ggtaaaatct
    23881 tatgttttct atattgctgg tttggcccag tctgcctgga ataagtagac cctttacaat
    23941 agaaagataa ttgtttttca gatttttatt tatttccagt tctgtgatga cttccctctc
    24001 agtaaacagc aatccgattc cagtggacct gaattattct aaacaaacaa acaatagcaa
    24061 caaactgtgg gggaaaattc agagttccca aaacataaat gaattagtat gggttgtcac
    24121 tcttttctcc tcacgctgtt tatgcttttg ttttaatcta gaaacattgt attcattgga
    24181 cattattttc agagaaaata actttttatc ttaacatctc atcccataga gtaaaatttc
    24241 aacaagtagt ctgactttta ataataagag tttatgatga tgaaaattca ttgggcaata
    24301 cattcacccc caaaaatttg tctggaaact tgtgttccaa aatagaatct gtggtttaga
    24361 ttttaaaata gatttaatat acattcctga aaaagagatt accttaacca caataaaaag
    24421 aagacaacac atattatttt cattcttaac tctagggaaa aaatgtaaac attagttgca
    24481 aaaagctatt ttagtgtatg gaaggatgtt cttgggaaaa aaataaaaac ataaaaggga
    24541 gagaggaaat aaagaaacca cggttttgtg aggtagtact ttcaaaggga tctatgtatc
    24601 tcagaagcta gtcaacaggt tttaagtatg tggaattgta gggttttata taaaaatgaa
    24661 gatacagtct ctactcttaa ggagattaaa acacaaacat ctcctcaatt gacaaggtct
    24721 ctttccatgc tttctatctg ggctaagaga cttatccttg aaaaatgttt gtgggtaaac
    24781 attttttact ctctgcttcc cattgtccta tcctcttctc catgcctgcc atccttaaga
    24841 ggactgaagc aggttataga ggaatcgcag ctgtgcactc ccactaccct catctcttca
    24901 gtcaccatgt cattaacagc atctctctct gctatattct ccctcctttc aatagcccag
    24961 ccttctttgt gtttcaaagc aggcaagaag cctgtctagc tagctgttta aattggaatt
    25021 cttctagagt ttgattcttc attttcttct ttctccacta aaattgattt cacatgtgtt
    25081 tgactcaagg gtgaacctgg tgtggttggt gctgtgggca ctgctggtcc atctggtcct
    25141 agtggactcc caggagagag gggtgctgct ggcatacctg gaggcaaggg agaaaaggta
    25201 cgtgttgacc cctattacat attgttgatg aactctagta aagaaggctg cacaaggatg
    25261 cccaagtttt cacaattctt ggcaggtggt ctggtagcat tttcatatct atctatatac
    25321 atttccctct accacctagc acctacacat ttctaaactc actaatctgg caagaagttc
    25381 cttgctacca tggaatttca cacaaacaga tggtgttgag taatacatga ggctcatttt
    25441 aatgccacta acaataatgc ctcatcctgt cctaattaat gggaagaagc tacattgaac
    25501 agctgtcaac catgctgctg cattagttat gccgtaagag tgatcaggcg ctgcagccca
    25561 ttgtgatgtt gccttacaat tctgtccaca tgaatctgta ccttgcttga ttatgcttca
    25621 ggagagtgta cggaaattag aaaagattgt ttaacaataa tctggaaatg gccttgaatt
    25681 attttttcct cattattttt ctcgattaac attctacaga atggtaagga atcgagacat
    25741 tgctaaaaat cttaaatgac tgaaggtatc atagcatctt ctgtaaaaaa gaaaaaaact
    25801 tcatattaat ttcgattcaa aattttggtc agaaaacaaa aagttgctct tgctttatac
    25861 tttcagggtg aacctggtct cagaggtgaa attggtaacc ctggcagaga tggtgctcgt
    25921 gtgagtagaa ttttgtttgt atgtttcttc gtacttggat ttttttttat gttgaattga
    25981 gaattttcca aattcgaact acacacactt tatttatcaa gtttaataaa ataatattcc
    26041 ttctctcctg ggctatgaca ataatatcat tttacagttc caaaggaaaa attaaaggga
    26101 tttaacctct ttgaaaataa tatccgaatt ttctaacttc ctagtgtcaa tgatccaact
    26161 acaaaactat agaccaaaag ctttaggttt aatagaatat taaatgatgc ttcaagtgat
    26221 aacagagatt aaaataaata aataaataag tctcctatgc tttaggaagc cgggacctct
    26281 aacaagattc tatagttatt caaacctact ccctagaaat ttatcaccca aagagcagcc
    26341 ccaaagatta gctgttaatg ccatgaagat gccaaagata atcccatgac agtctaatta
    26401 ccttatctcg tatgtcagcc tcatgggtct tctaggccac agtcggcctg gattccttta
    26461 ttcacctctc cttcagagct gaaaactgac tgtagcacat ctgtaatagt ctttcttttg
    26521 aatcacatag ttctaacagt ttcaaacaag gctactcatt tgctgctctc cagggaattt
    26581 tacaatagcg gaaagttcag atctcccaaa tttctgacct gctatgactt acacatttcc
    26641 ataaccttta ttactggagt accctccttc tgagagtggc ttctaatagt cttgttaatt
    26701 agaaccaaaa tacatcagag gccttctaga tatccaacca gagtgcagtg aaagtgttca
    26761 gtcactgtat aagcacagaa aaaaagaatg acaaggttca cttttgatga tacggggtgt
    26821 tattaataag acatgtttcc tttttggtac tagggtgctc atggtgctgt aggtgcccct
    26881 ggtcctgctg gagccacagg tgaccgggta agcatgcatt ttcactaagc caacagcaat
    26941 atctaaaatt tcccgccttc cctagtccca aagagcccca gcaattcatt tttatggctt
    27001 ggtataaagc ctacttattt aaaaacctag ctattgtgat agagcagcag gaaacaaatg
    27061 ctgtgtgttt aaaattactt ttcccttcct atagatttgc cagctatctg atctatactc
    27121 taatccctag catttgtttt aaagtctctc catgttgcgc attaacaata tcctaatgca
    27181 ctgaggcttc tcaaagcctt caattattac caaaaaatca ataaaataca tagtgtgccc
    27241 atttcacatt gaactctcca cttaaaatag atcttattta ttgtattgca aagattgcca
    27301 caaatagatc agccccgtgt ccatctaaaa attaaaatgt cctcctcctg gtattgtagg
    27361 cactgattta tagtgttttc tcaagtgtat aacccatacc acttaacccc caaaatgaat
    27421 atagcattaa gtaaaaatcc acttcatttt actctgtgag atgtgcgtca gttatctctt
    27481 ccaaggcaac taagactctg tctgtccacc actgttctct ctccctccca gttctttgag
    27541 catctatgtc aggcacatta acagattcat ctttggtccc attatagggc gaagctgggg
    27601 ctgctggtcc tgctggtcct gctggtcctc ggggaagccc tgtaagtaag aacctgggtc
    27661 attttgtata ctcacacctc acaatgttta gacattgatg aacctaggat tgataacaca
    27721 tttttaaatc ccttctccca cctagggtga acgtggcgag gtcggtcctg ctggccccaa
    27781 cggatttgct ggtccggctg tgagtatcac ataatgaaga ttaatctgaa aacatcctaa
    27841 gttggggagt agagtgggtc ggaataccag agctgtaact gtttatttcc aacagggtgc
    27901 tgctggtcaa ccgggtgcta aaggagaaag aggaggcaaa gggcctaagg gtgaaaacgg
    27961 tgttgttggt cccacaggcc ccgttggagc tgctggccca gctgtaagtt gaattcactg
    28021 gtggtccaca cagcagctac ccattagatc ttccaattaa atatatatcc gtcaagtgcc
    28081 tgctatgcaa cagggaatat accagataga agatggaaaa taacggaagg attaacattt
    28141 gcacactgct ttacaaagta taaaagtttc atgaatattg ttttatttta attctctgat
    28201 aacctcataa gggtggtaat attgaagaac attctgacac agatagtcat tttttatttc
    28261 tatattttct tctaagagat gcgggaatga tccacttgaa gaaaagagta gcatttacaa
    28321 gggtttgttt gtgatttgac tccatctttt ttgtttgcat ttagggtcca aatggtcccc
    28381 ccggtcctgc tggaagtcgt ggtgatggag gcccccctgt gagtattaca atggacctct
    28441 cgccgctttt cttttttcag aatctattaa ggacacttga aagttttgaa atttttggta
    28501 aatttggact accatgagga aacttttgag attcaagttc attctattca gagcaattcc
    28561 gatattgatg ttaacttgaa ctcagctgga actcagtgta tgttgctatc agctcacttg
    28621 aggtaataac caaggtgggc cctaggcagt ttaattgtaa agtcggaaaa aatattcctt
    28681 ttggcgttta ttaatatgcc ccttcttctg cctgaccatg tccttctcct ttgcaggcaa
    28741 tgctatcaca acaattctct agagacccag agctccccaa aaatgaactt tactgacttc
    28801 ttctctcact ggacagtgct gaattatcta ggtcatttgt tattcttttg tccatgaaca
    28861 ccattaccta ttaagtgtcc atttccttac cactcagcca ggtggtaaag atagttatta
    28921 atgtatacac attaatgtgt aataatgaca tagtgtctta tcttcatacc tttacaacca
    28981 taagataata tgtcagcatt tcagaaagga ccatccaaac cttaacgcaa aatatgggca
    29041 ttgcaactgg taatatgctg gtaaggaaga tgtgtggaga aggagggcct tcagggtcct
    29101 ggctaaataa tgccctatat gaagctgcct gattttccaa aacaaagaaa ttcccatctt
    29161 acccaaattc ttggagttga tgttgactgt ggaattctaa tgtgcttggc tcttagggta
    29221 tgactggttt ccctggtgct gctggacgga ctggtccccc aggaccctct gtaagtaaat
    29281 cactgtaaac gtgtcttcat ttactctagc caaaaggcct ggcttctgat aggaaactgg
    29341 taagaaactc ttcatgaaaa cacatcacta atattcgcta ttactctcct ggtctgaagt
    29401 cagcttttct gaaccattaa ggtatttcat cacaagttat attttataat atcagtttaa
    29461 gaggctttta ttcatgtgaa caccagtccc ctttcagggg catggtcttt ttgaaaaaaa
    29521 aaaacaaaaa aacgaacagt tttagccaca tatcagatat ttctatatct aattatcctt
    29581 tatggctaac attctgcctc cattgttaag gtataattgt tcctgaattt aaaggtggtt
    29641 tggcctctaa tttaattctg attcagactc tcctgtcagg actcaagaaa atttaattaa
    29701 ttaccaagga ttaagtcttc tggttaaggt ttctgggaaa aaaaaatagc aaagatgttg
    29761 atttcttgga atccttttac aggttcataa cagaaaaatc ttcattccct gtaggcattt
    29821 aattaaacct agttgagaag tgtgtgggat tcctcaatta tgaacaaaac acgtatattg
    29881 gctttcttta aaaaaaaaaa aaagaagaaa aaagaaaagg caaagtcctt cgaaactcag
    29941 agtcccattc atttatcatt aactcctatc attctacata gttctgattc caatatgcca
    30001 gggtaccagt ggcatgacat tgtttttcct catagaaatt tgccatagtc tctcctccat
    30061 tatttggttg gttacagcct cataaaggaa gacaggagtt gcttctttct gcaagaaaga
    30121 aggttaaaaa ctataaatat ttcccccaaa tggccagggt attattttat tgcatcacat
    30181 tgtttgcatc ttaagatcta gaatctttgc tgctctcttc caggcccttg gtgattaaca
    30241 gaaaggaaat gaccttgtac atttgctcat agggtatttc tggccctcct ggtccccctg
    30301 gtcctgctgg gaaagaaggg cttcgtggtc ctcgtggtga ccaaggtcca gttggccgaa
    30361 ctggagaagt aggtgcagtt ggtccccctg gcttcgctgg tgagaagggt ccctctggag
    30421 aggctggtac tgctgtaagt gatttccaac tcctctttct taatacctta tgctgaatta
    30481 aaataaagcc cctacacaga tcttcaagtg gcatctattt gttgatgagt attgcaggct
    30541 ctcaagtaga gctcagttga gccaggaaat ctgtccagca cacactgagg ggctgtggct
    30601 tccaagatgc tcagaaagca caaatcggga agacaataaa tgagggaact cagttttatc
    30661 acaaaaccct taaagctatt gaaggcacct tactggtacc aggattagaa cagagtccca
    30721 ttgctgtggc catcctacta catattaatc aatctcagta ggctaccaat ttcttaaaca
    30781 tacactgtcc agtattagtg ctactctgaa aggtgcccct attagacctt agaggccaaa
    30841 gtcaaaattt gcttcctttt gatatactga ttttactgat ttcctttttg tttttgtttt
    30901 ttgtttttgt ttttgttttt ttgttttggg atggagttcc cctctgttgc ccaggctgga
    30961 gtgcagtggc acgatctcag ctcactgcga cttccgctcc cagttcaagt aattatcttg
    31021 tctcagcctc cgagtagctg ggactacagg cacacaccat catgcctagc taatttttgt
    31081 attttagtaa agacggggtt tcaccatatt ggtcaggctg gtctcgatct cctgacctca
    31141 ggtgatccac ccaccttgac ctcctaaagt gctgggatta cacatgtgag ccaccccacc
    31201 cagcctgatt tcctttcctt tgtgtatata cccagcagtg tgattgctgg atcttatggt
    31261 agttctattt ttagtttttt gaggaacccc tcctactatg tacaactatt atgtatccat
    31321 aacaatttaa atttttttat ttgtttccct gcctagaggc tataaaaact ctatttcacc
    31381 accccaagtg tctttataaa tctcaaccac atatttttaa atgttgtgcc attggtctca
    31441 aggatgaatc agatacaaaa gtattcatgc caagatgtaa actcaccgtc atcactagag
    31501 aaaagatatc caaggatatg tcctagtaat aggaggtcat tagccttttt ctaagctgaa
    31561 gacagtttat tctcacaatc ttcaagccaa cctgtgttat cacctagggt cttacccata
    31621 atactcagta ttttttctct atttagggac ctcctggcac tccaggtcct cagggtcttc
    31681 ttggtgctcc tggtattctg ggtctccctg gctcgagagg tgaacgtggt ctacctggtg
    31741 ttgctggtgc tgtggtgagt gcttgacagt attctgactc cattaacata agaaaagatt
    31801 ttaaaagctg ccacttcaaa tgtgacagat tgatcactga ataacttcac ttaagatttt
    31861 tattcatggc attttcttta tacagatcac atgtcactta tctaagaagc tttaatacca
    31921 ccttacttag acacacacta taaagacaca gcttaattat gcagaatgat ttttggttct
    31981 ttccacgcac ttaggaacga tacaatctct aattgcgttt actcctctgc aatatgaaat
    32041 gctggcatca tttatcctgt aggaagaatg aaactctgga agttctgaat cgttccatta
    32101 aaccttatac gtgacaacaa ctagaaacca tctcatctcc ataaaatata tcaacttttt
    32161 gaattcattt catttgggat actgaatgac acgaggctca ctttttacag agcaacatcc
    32221 cgtgattaca taaagctggc catctacatg tggagaagga gggcagagat gatactaatg
    32281 atacttctta ccattgtgtg acccattcac attcaattta ccttcttcct tcaaactaga
    32341 atctcctgag tagggttgtt ttggagggga aggttagcat tccatcgaat aaggggaatg
    32401 tcattttatc ttctctgcct gtttagggtg aacctggtcc tcttggcatt gccggccctc
    32461 ctggggcccg tggtcctcct ggtgctgtgg gtagtcctgg agtcaacggt gctcctggtg
    32521 aagctggtcg tgatgtgagt ccaacacttg gtttgtaaaa taaaactgag caggatttca
    32581 ttgtgtgaaa ctttatgtcc tgagctgagg ttctcttctt ccaaatttct gaacaagatg
    32641 gtcaagcttc tccatagtat ctacacctag tactgaaaat atgaaaattg cttaggccaa
    32701 agaatgggct tttcaatagc acactgcaaa actggcccaa gtatttaaaa catctctaaa
    32761 aaatatctag gttggcaggt ttttatccct agttttaaca gtctgaaaga gggttcgtta
    32821 ctgagcactg gaagtgatga agacagagta gctacaacat aggggctggt aggcagcaga
    32881 gcctcaccaa cagccttaat ttgtgtggtg tcttcacagg gcaaccctgg gaacgatggt
    32941 cccccaggtc gcgatggtca acccggacac aaggtcagta cacttttcat ctttctctaa
    33001 ttcaaaagtg attaaaatgc aacccagatt gatgctaagc ttcattttgc ctttggtagg
    33061 gagagcgcgg ttaccctggc aatattggtc ccgttggtgc tgcaggtgca cctggtcctc
    33121 atggccccgt gggtcctgct ggcaaacatg gaaaccgtgg tgaaactgta agtttgtgaa
    33181 taccagtccc tcagtgcagc attctcgtgg gcttcacttc tgacttcccc acacttgggg
    33241 atggtggagg agtggggagg ggtatcttgg gcctagctaa gttgtgtttt tctttttcat
    33301 ttcacagggt ccttctggtc ctgttggtcc tgctggtgct gttggcccaa gaggtcctag
    33361 tgtatgtaca tgctgaagat ttctttgcaa cactaacatt tagagagaat cagtccaaaa
    33421 catctgttaa gaaaataaac aatatatcag ctagacttaa tattttttaa aaatttcagt
    33481 ccatgctgag aattgataca aataacttga gctattttaa atctcttatg cttgtttgta
    33541 ttaaacaatt acaaggatct agccacttta cagatagcac aactaaagca gattaccagc
    33601 agaggtgaga gcctagctaa accattacat gtcctgagtt acctttgtaa acgaattaag
    33661 cagtatttgt ggtgaagtga gtgccatttt tttaaaacgg taagtcttat ccatccttct
    33721 gtttctttat agggcccaca aggcattcgt ggcgataagg gagagcccgg tgaaaagggg
    33781 cccagaggtc ttcctggctt caagggacac aatggattgc aaggtctgcc tggtatcgct
    33841 gtaagtaaac tgtagccatc tcgcacataa actgatcctg aaggccttca gctcagaagg
    33901 attttcatat tttcactgct attgttccag tatagcctat ataatatcca tttcccattc
    33961 tctggctaac tccatctcac tcttggaggt aatgctattt catgccaaca tgaaaggtga
    34021 ggattaaggg agatagaaat atacaataca ataaaatctc ctggtaacaa tgtccttcaa
    34081 ccccacttaa aataaacata attagaggaa tgactaatat tgcactgctg aaataggttg
    34141 tgaaaaaaaa ttgaatataa tagacataat gggagaaaag agccccactt tacattttca
    34201 attttctcaa tccggagtcc atttaactaa agtttcccat tgaatttgga aaaaaaaaaa
    34261 atatgtctct tgacatgtgc tctgaaagtg tgattttcct cttctgtctt taaagggtca
    34321 ccatggtgat caaggtgctc ctggctccgt gggtcctgct ggtcctaggg taggtggact
    34381 caagagaaga cagttcatct ctgaaataga ggctaaagcg agcagtgagc cccaggctgc
    34441 tgctcccttg gtgggattca ccagctcaca tgtacctggt gtctgtcttc cttagggccc
    34501 tgctggtcct tctggccctg ctggaaaaga tggtcgcact ggacatcctg gtacggttgg
    34561 acctgctggc attcgaggcc ctcagggtca ccaaggccct gctgtaagta tgatttgggg
    34621 aaataataaa gaagatcacg gacctaagga atgttttctt cagactaaac caagacaact
    34681 ttgacaaccc attaaagtta gccccatttc aatatatcct ctaaaatatc tggaaattgt
    34741 ctatatgcaa tgggcttgtt aagtccatcc catgcaagtg tgcctggggg ctcgttattt
    34801 atttatgtga acttgattat tttttactga tgagaacatg cttccgtgtg aagctcaact
    34861 gaaaatctgc tgccatggat gtctctcact gtaaaaaaat ataaagcctc tcctatctaa
    34921 ctttcacctt tgcagggccc ccctggtccc cctggccctc ctggacctcc aggtgtaagc
    34981 ggtggtggtt atgactttgg ttacgatgga gacttctaca gggctgacca gcctcgctca
    35041 gcaccttctc tcagacccaa ggactatgaa gttgatgcta ctctgaagtc tctcaacaac
    35101 cagattgaga cccttcttac tcctgaaggc tctagaaaga acccagctcg cacatgccgt
    35161 gacttgagac tcagccaccc agagtggagc agtggtaggt caagatgtcc agaccagact
    35221 gacccttctc acaagttgag cttttcaaaa ttagtttcca ttgacattta gagtgaaaat
    35281 gcatttgggt aaagattaca ttatgtgaaa tcacacccaa ttaatggagc gtcatcttct
    35341 cccaaccagc acccaacctc atttccctta aaatgtattt ttgcactttt catagtaata
    35401 agtaccctga tttgattttt catggaggag gggagggaag gaactgtcta atcttaaaaa
    35461 tagccaccct cttcctctta aatatggggt agacaatcaa aaatgttact tatgagagtc
    35521 agtatctttc attagttatt attagaatct gtgttctgct caatgagaag tttcatgatc
    35581 tgaatgttat tttcttaaaa ggttactact ggattgaccc caaccaagga tgcactatgg
    35641 aagccatcaa agtatactgt gatttcccta ccggcgaaac ctgtatccgg gcccaacctg
    35701 aaaacatccc agccaagaac tggtatagga gctccaagga caagaaacac gtctggctag
    35761 gagaaactat caatgctggc agccaggtga ggaatcccac aaacacctct ccttctgcta
    35821 aataatattt tggtaggact gtttgttaat tatctgcatt ttaatctctg acaaaaatgg
    35881 gcttattaaa aaaagacctg ttcctttcct gggttccaat tttgtgccta aattgcacat
    35941 tagaagatgg attgattgga cacatccatg taattcaaag ttattattca aatttgactt
    36001 aattggtaat cattgaaaaa actgactaat gtcatttagt gtgaaggagc actggccagc
    36061 tatatgccac actcatacat atgcattttc agaatgtgag cagcttttct gaatttttaa
    36121 tcaaaccttt tcaccaactt tactgaatgc ctactggaat tccataaatt acaaaatgac
    36181 agaaaaagaa aaatgtcaga atttctacct cctcattctc ttattctaaa gaagaacgat
    36241 atgcaaaaag gattaattga aacagataac ttttttagat gaccttgcct cagtctagta
    36301 ggtcttatgt tcatctaggt aactgatact tcaaagacaa gtgaattaag ttttctttaa
    36361 aagtaccctt ttcctaagct tggatctgag tctactcttc ctgagatctt tttttttctt
    36421 tttttttttt ttcatgtttg actcttagta tctgagtcct tctccactta actggaattt
    36481 catcctattt tctgtagttt gaatataatg ttgaaggagt gacttccaag gaaatggcta
    36541 cccaacttgc cttcatgcgc ctgctggcca actatgcctc tcagaacatc acctaccact
    36601 gcaagaacag cattgcatac atggatgagg agactggcaa cctgaaaaag gctgtcattc
    36661 tacagggctc taatgatgtt gaacttgttg ctgagggcaa cagcaggttc acttacactg
    36721 ttcttgtaga tggctgctct gtaagtaata gtgaaatatg ggaatagctt tgggaagtgg
    36781 gatggagggg gttctaactt agactgcccc caaggggggt ctaaaggggg gttaaaagaa
    36841 cagaagaatg agagaactaa cttatttcat aagtaaattc agtttttgta tgtattttat
    36901 atttatttat ttatacgtat taatttcgta cttaaattca gatgataaat tcagagtatt
    36961 cttatcagat agtgccttct gaaatgctga aatgtatact atgtccatgc attgtttttt
    37021 ctttagcatg ttttttaaat ggtaatgtgt gcccagaact taaaatttct tgagcttcag
    37081 tggcctaaac tataatttat agttatgtgt attttatttt acttattagt atggctacat
    37141 ttaactttta atgctttttc tacaatatgc tataaatata agaaaaatta aaattcacta
    37201 acagcaagac tacataccca cccaggtccc gctcccaaag acacacatag agggacatac
    37261 acacaacaat cctaaaaatg actttgtaga gataggtcac ttggaatgtg tgttgaaatg
    37321 ttgttggttt ttttggttgg tttgtttgtt tgttttttgt tagactgata gggagcccct
    37381 cccactaaag acacccttga tactgttatt tcaaggatga acttatttat ctgggacaga
    37441 catcttcaga atgacacatg ccaaacagtg gttcttatta aatcaaaggt tcagatatta
    37501 tcagattcag aaatagtgat gctttgtgta tctattttct tctctttaaa cagaaaaaga
    37561 caaatgaatg gggaaagaca atcattgaat acaaaacaaa taagccatca cgcctgccct
    37621 tccttgatat tgcacctttg gacatcggtg gtgctgacca tgaattcttt gtggacattg
    37681 gcccagtctg tttcaaataa atgaactcaa tctaaattaa aaaagaaaga aatttgaaaa
    37741 aactttctct ttgccatttc ttcttcttct tttttaactg aaagctgaat ccttccattt
    37801 cttctgcaca tctacttgct taaattgtgg gcaaaagaga aaaagaagga ttgatcagag
    37861 cattgtgcaa tacagtttca ttaactcctt cccccgctcc cccaaaaatt tgaatttttt
    37921 tttcaacact cttacacctg ttatggaaaa tgtcaacctt tgtaagaaaa ccaaaataaa
    37981 aattgaaaaa taaaaaccat aaacatttgc accacttgtg gcttttgaat atcttccaca
    38041 gagggaagtt taaaacccaa acttccaaag gtttaaacta cctcaaaaca ctttcccatg
    38101 agtgtgatcc acattgttag gtgctgacct agacagagat gaactgaggt ccttgttttg
    38161 ttttgttcat aatacaaagg tgctaattaa tagtatttca gatacttgaa gaatgttgat
    38221 ggtgctagaa gaatttgaga agaaatactc ctgtattgag ttgtatcgtg tggtgtattt
    38281 tttaaaaaat ttgatttagc attcatattt tccatcttat tcccaattaa aagtatgcag
    38341 attatttgcc caaagttgtc ctcttcttca gattcagcat ttgttctttg ccagtctcat
    38401 tttcatcttc ttccatggtt ccacagaagc tttgtttctt gggcaagcag aaaaattaaa
    38461 ttgtacctat tttgtatatg tgagatgttt aaataaattg tgaaaaaaat gaaataaagc
    38521 atgtttggtt ttccaaaaga acatattgag taaaattcct tgcttcaatg ctctttgcaa
    38581 tataaatatg catctctacc agccattaga ccaagtgcct ctgattagat agaaattatg
    38641 caaaaagggc agtttggtgt ggtagaagag cagagaacga gg
//
