Program 2019

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REMEMBER TO BRING A LAPTOP COMPUTER FOR EXERCISES

Lectures and exercises will take place at the Section for Bioinformatics at the Technical University of Denmark, Building 208, Room 062 in Lyngby (map).

The courses has two main parts, the first half is lectures and exercises and the last half is project work ending with the exam on Thursday 27th of June.

This term we will be using Piazza for class discussion. The system is highly catered to getting you help fast and efficiently from classmates, the TA, and myself. Rather than emailing questions to the teaching staff, I encourage you to post your questions on Piazza here

Course Program - June 2019


Thursday, June 6


Introduction - Next Generation Sequencing

9.00-9.30
Introduction to course & Pre-test (Lecture slides) (Pre-test)
Gisle Vestergaard
9.30-10.00
Introduction to NGS (Lecture slides)
Gisle Vestergaard
10.00-10.45
2nd and 3rd generation NGS Technologies (Lecture slides)
Gisle Vestergaard
10.45-11.00
Break
11.00-12.00
Tech talk group formation and group work (Lecture slides) (Student Groups)
Gisle Vestergaard
12.00-13.00
Lunch Break
13.00-13.30
Exercise: Logging on to our Computerome cloud (Logging on to Cloud system)
Gisle Vestergaard, Katrine Højholt
13.30-14.15
Introduction to UNIX (Lecture slides) (Exercise) (Unix Notes)
Peter Wad Sackett, Gisle Vestergaard
14.15-14.30
Break
14.30-15.30
Introduction to UNIX (Lecture slides) (Exercise) (Unix Notes)
Peter Wad Sackett, Gisle Vestergaard, Katrine Højholt
15.30-16.00
First look at data (First look exercise)
Gisle Vestergaard, Katrine Højholt


Friday, June 7


Data pre-processing & Genomic Epidemiology

9.00-10.45
Data basics (Lecture slides) (Data basics exercise) (Data basics solution)
Gisle Vestergaard, Katrine Højholt
10.45-11.00
Break
11.00-12.00
Data pre-processing (Lecture slides) (Data Preprocess exercise) (Data Preprocess solution)
Katrine Højholt
12.00-13.00
Lunch Break
13.00-14.00
Exercise: Genomic Epidemiology (Genomic epidemiology exercise) (Genomic epidemiology solution)
Gisle Vestergaard, Katrine Højholt
14.00-16.00
Case story: Genomic Epidemiology (Lecture)
Pimlapas Leekitecharoenphon (Shinny)


Monday, June 10


Whit Monday - No teaching!


Tuesday, June 11


Alignment & Genotyping

9.00-9.45
Alignment (Lecture slides)
Gisle Vestergaard
9.45-10.00
Break
10.00-12.00
Exercise: Alignment (Alignment exercise) (Alignment solution)
Gisle Vestergaard, Jakob Nissen, Katrine Højholt
12.00-13.00
Lunch Break
13.00-13.25
Functional Human Variation
Jose Izarzugaza (Txema) (Lecture slides)
13.25-14.00
Alignment postprocessing & variant calling (Lecture slides)
Gisle Vestergaard
14.00-14.15
Break
14.15-16.00
Exercise: Postprocessing & variant calling (Postprocess exercise) (Postprocess solution) (SNP calling exercise) (SNP calling solution)
Gisle Vestergaard, Jakob Nissen, Katrine Højholt

Wednesday, June 12


de novo assembly & Metagenomics

9.00-9.45
Lecture: de novo assembly (Lecture slides) (Handout)
Gisle Vestergaard
9.45-10.00
Break
10.00-12.00
Exercise: de novo assembly (denovo exercise) (denovo solution)
Gisle Vestergaard, Jakob Nissen, Katrine Højholt
12.00-13.00
Lunch Break
13.00-13.45
Metagenomics & Binning (Lecture slides)
Jakob Nissen
14.00-16.00
Exercise: Metagenomic de novo assembly (Metagenomic assembly exercise) (Metagenomic assembly solution)
Gisle Vestergaard, Jakob Nissen, Katrine Højholt


Thursday, June 13


Quantitative Metagenomics and Test

9.00-9.45
Lecture: Quantitative Metagenomics (Lecture slides)
Gisle Vestergaard
9.45-10.00
Break
10.00-12.00
Exercise: Quantitative Metagenomics (Exercise) (Solution)
Gisle Vestergaard, Jakob Nissen
12.00-13.00
Lunch Break
13.00-13.45
Recap Test (Test)
13.45-14.00
Break
14.00-16.00
Time to work on this weeks exercises
Gisle Vestergaard, Jakob Nissen, Katrine Højholt


Friday, June 14


RNA-seq and Cancer-seq

9.00-9.45
Lecture: RNAseq (Lecture slides)
Fransesca Bertolini
9.45-10.00
Break
10.00-12.00
Exercise: RNAseq (Exercise) (Solution)
Francesca Bertoloni, Gisle Vestergaard, Katrine Højholt, Jakob Nissen
12.00-13.00
Lunch Break
13.00-13.45
Lecture: Cancer-seq (Lecture slides)
Jose Izarzugaza (Txema)
14.00-16.00
Exercise: Cancer-seq (Exercise)
Jose Izarzugaza (Txema), Gisle Vestergaard

Monday, June 17


Ancient DNA & Tech talks

9.00-10.00
Ancient DNA (Lecture slides)
Martin Sikora
10.00-12.00
Exercise: Ancient DNA (Exercise)
Martin Sikora, Gisle Vestergaard
12.00-13.00
Lunch Break
13.00-16.00
Tech talk work & Presentations
Gisle Vestergaard


Tuesday, June 18


Project work

9.00-9.45
Projects & Group formation (Lecture slides Examples from previous courses)
Gisle Vestergaard, Jakob Nissen, Katrine Højholt
9.45-10.45
Projects & Group formation
Gisle Vestergaard, Jakob Nissen, Katrine Højholt
10.45-11.00
Break
11.00-12.00
Project work
Gisle Vestergaard, Jakob Nissen, Katrine Højholt
12.00-13.00
Lunch Break
13.00-16.00
Project work/Prepare presentations for tomorrow


Wednesday, June 19


Project work & Project Presentations

9.00-12.00
Project work
Gisle Vestergaard, Katrine Højholt
12.00-13.00
Lunch Break
13.00-14.00
Project Presentations
Gisle Vestergaard


Thursday, June 20


Project work

9.00-16.00
Project work
13.00-15.00
Project work/Office hours
Gisle Vestergaard, Katrine Højholt


Friday, June 21


Project work

9.00-16.00
Project work
13.00-15.00
Project work/Office hours
Jose Izarzugaza (Txema), Katrine Højholt


Monday, June 24


Project work

9.00-16.00
Project work
13.00-15.00
Project work/Office hours
Gisle Vestergaard, Jakob Nissen, Katrine Højholt


Tuesday, June 25


Project work

9.00-16.00
Project work
13.00-15.00
Project work/Office hours
Gisle Vestergaard, Jakob Nissen, Katrine Højholt


Wednesday, June 26


Project Work & Poster Printing

Print your poster, it is possible to print in DTU library for 16-30kr.
Poster guide & requirements
10.00-12.00
Q&A: Practical information about the Exam
Project work/Office hours
Gisle Vestergaard, Jakob Nissen, Katrine Højholt



Thursday, June 27


Poster session - in the hall in front of the Section for Bioinformatics (building 208)

10.00-14.00
Poster session part (exam)